Porphyrin as diagnostic and therapeutic agent

N Tsolekile, S Nelana, OS Oluwafemi - Molecules, 2019 - mdpi.com
The synthesis and application of porphyrins has seen a huge shift towards research in
porphyrin bio-molecular based systems in the past decade. The preferential localization of …

Advancements of Porphyrin‐Derived Nanomaterials for Antibacterial Photodynamic Therapy and Biofilm Eradication

S Chen, B Huang, J Tian… - Advanced Healthcare …, 2024 - Wiley Online Library
The threat posed by antibiotic‐resistant bacteria and the challenge of biofilm formation has
highlighted the inadequacies of conventional antibacterial therapies, leading to increased …

Photodynamic antimicrobial chemotherapy: advancements in porphyrin-based photosensitize development

J Oyim, CA Omolo, EK Amuhaya - Frontiers in chemistry, 2021 - frontiersin.org
The reduction of available drugs with effectiveness against microbes is worsening with the
current global crisis of antimicrobial resistance. This calls for innovative strategies for …

Synthesis and applications of porphyrin-biomacromolecule conjugates

P Pathak, MA Zarandi, X Zhou… - Frontiers in …, 2021 - frontiersin.org
With potential applications in materials and especially in light-responsive biomedicine that
targets cancer tissue selectively, much research has focused on develo** covalent …

Carbon dot-DNA-protoporphyrin hybrid hydrogel for sustained photoinduced antimicrobial activity

S Kumari, SR Prasad, D Mandal, P Das - Journal of colloid and interface …, 2019 - Elsevier
An assembly of hybrid hydrogel derived from Carbon Dot (CD), Protoporphyrin IX (PpIX) and
DNA is reported here. PpIX and CD were covalently conjugated to 5′-phosphate termini of …

Latest trends on photodynamic disinfection of Gram-negative bacteria: Photosensitizer's structure and delivery systems

N Maldonado-Carmona, TS Ouk… - … & Photobiological Sciences, 2022 - Springer
Antimicrobial resistance is threatening to overshadow last century's medical advances.
Etiological agents of previously eradicated infectious diseases are now resurgent as …

Biomass derived self-assembled DNA-dot hydrogels for enhanced bacterial annihilation

S Nayak, P Kumar, R Shankar, AK Mukhopadhyay… - Nanoscale, 2022 - pubs.rsc.org
Nanotization of biomass for interesting biomedical applications is still in the nascent stage
with no visible market available products. While products derived from biomass DNA and …

Learning from nature: bioinspired strategies towards antimicrobial nanostructured systems

G Vitiello, B Silvestri, G Luciani - Current Topics in Medicinal …, 2018 - ingentaconnect.com
Microbial contamination still remains a major issue of the modern era, due to the widespread
of drug-resistant pathogens. This has prompted researchers to come up with novel …

A systematic overview of strategies for photosensitizer and light delivery in antibacterial photodynamic therapy for lung infections

MO Shleeva, GR Demina, AP Savitsky - Advanced Drug Delivery Reviews, 2024 - Elsevier
Antimicrobial photodynamic therapy (aPDT) emerges as a viable treatment strategy for
infections resistant to conventional antibiotics. A complex interplay of factors, including …

Adsorption of DNA oligonucleotides by self-assembled metalloporphyrin nanomaterials

J Wang, Z Wang, PJJ Huang, F Bai, J Liu - Langmuir, 2022 - ACS Publications
Porphyrin assemblies have controllable morphology, high biocompatibility, and good optical
properties and were widely used in biomedical diagnosis and treatment. With the …