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The tumor-on-chip: Recent advances in the development of microfluidic systems to recapitulate the physiology of solid tumors
G Trujillo-de Santiago, BG Flores-Garza… - Materials, 2019 - mdpi.com
The ideal in vitro recreation of the micro-tumor niche—although much needed for a better
understanding of cancer etiology and development of better anticancer therapies—is highly …
understanding of cancer etiology and development of better anticancer therapies—is highly …
Mechanistic understanding of curcumin's therapeutic effects in lung cancer
Lung cancer is among the most common cancers with a high mortality rate worldwide.
Despite the significant advances in diagnostic and therapeutic approaches, lung cancer …
Despite the significant advances in diagnostic and therapeutic approaches, lung cancer …
Metabolic reprogramming in breast cancer results in distinct mitochondrial bioenergetics between luminal and basal subtypes
P Lunetti, M Di Giacomo, D Vergara… - The FEBS …, 2019 - Wiley Online Library
Mitochondrial dysfunction is a key feature of cancer and is frequently associated with
increased aggressiveness and metastatic potential. Recent evidence has brought to light a …
increased aggressiveness and metastatic potential. Recent evidence has brought to light a …
Unraveling the anticancer effect of curcumin and resveratrol
Resveratrol and curcumin are natural products with important therapeutic properties useful
to treat several human diseases, including cancer. In the last years, the number of studies …
to treat several human diseases, including cancer. In the last years, the number of studies …
The cancer microbiota: EMT and inflammation as shared molecular mechanisms associated with plasticity and progression
With the advent of novel molecular platforms for high‐throughput/next‐generation
sequencing, the communities of commensal and pathogenic microorganisms that inhabit the …
sequencing, the communities of commensal and pathogenic microorganisms that inhabit the …
Proteomics-based identification of dysregulated proteins in breast cancer
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
Glutamine-fructose-6-phosphate transaminase 2 (GFPT2) Is upregulated in breast epithelial–mesenchymal transition and responds to oxidative stress
Q Wang, ST Karvelsson, A Kotronoulas… - Molecular & Cellular …, 2022 - ASBMB
Breast cancer cells that have undergone partial epithelial–mesenchymal transition (EMT)
are believed to be more invasive than cells that have completed EMT. To study metabolic …
are believed to be more invasive than cells that have completed EMT. To study metabolic …
Anti-metastatic effect of pyruvate dehydrogenase kinase 4 inhibition in bladder Cancer via the ERK, SRC, and JNK pathways
EH Lee, JW Chung, E Sung, BH Yoon, M Jeon… - International Journal of …, 2022 - mdpi.com
Bladder cancer is a common global cancer with a high percentage of metastases and high
mortality rate. Thus, it is necessary to identify new biomarkers that can be helpful in …
mortality rate. Thus, it is necessary to identify new biomarkers that can be helpful in …
Epithelial–Mesenchymal Transition Associated with Head and Neck Squamous Cell Carcinomas: A Review
R González-González, G Ortiz-Sarabia… - Cancers, 2021 - mdpi.com
Simple Summary Mesenchymal conversion occurring in malignant epithelial neoplasms is
undesirable in tumors since it promotes more aggressive tumor behavior. This phenomenon …
undesirable in tumors since it promotes more aggressive tumor behavior. This phenomenon …
[HTML][HTML] Translating epithelial mesenchymal transition markers into the clinic: Novel insights from proteomics
The growing understanding of the molecular mechanisms underlying epithelial-to-
mesenchymal transition (EMT) may represent a potential source of clinical markers. Despite …
mesenchymal transition (EMT) may represent a potential source of clinical markers. Despite …