Development of the human placenta

MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

Regulation of placental development and its impact on fetal growth—new insights from mouse models

L Woods, V Perez-Garcia, M Hemberger - Frontiers in endocrinology, 2018 - frontiersin.org
The placenta is the chief regulator of nutrient supply to the growing embryo during gestation.
As such, adequate placental function is instrumental for developmental progression …

Placental origins of chronic disease

GJ Burton, AL Fowden… - Physiological …, 2016 - journals.physiology.org
Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

The placenta‐brain‐axis

CS Rosenfeld - Journal of neuroscience research, 2021 - Wiley Online Library
All mammalian species depend on the placenta, a transient organ, for exchange of gases,
nutrients, and waste between the mother and conceptus. Besides serving as a conduit for …

Sex-specific placental responses in fetal development

CS Rosenfeld - Endocrinology, 2015 - academic.oup.com
The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

Single nuclei RNA-seq of mouse placental labyrinth development

B Marsh, R Blelloch - Elife, 2020 - elifesciences.org
The placenta is the interface between mother and fetus in all eutherian species. However,
our understanding of this essential organ remains incomplete. A substantial challenge has …

Initial sequencing and comparative analysis of the mouse genome

European Bioinformatics Institute: Birney Ewan 3 … - Nature, 2002 - nature.com
The sequence of the mouse genome is a key informational tool for understanding the
contents of the human genome and a key experimental tool for biomedical research. Here …

Natural killer cells and pregnancy

A Moffett-King - Nature Reviews Immunology, 2002 - nature.com
The fetus is considered to be an allograft that, paradoxically, survives pregnancy despite the
laws of classical transplantation immunology. There is no direct contact of the mother with …

The uterine spiral arteries in human pregnancy: facts and controversies

R Pijnenborg, L Vercruysse, M Hanssens - Placenta, 2006 - Elsevier
Uterine spiral arteries play a vital role in supplying nutrients to the placenta and fetus, and
for this purpose they are remodelled into highly dilated vessels by the action of invading …

Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia

L Ji, J Brkić, M Liu, G Fu, C Peng, YL Wang - Molecular aspects of medicine, 2013 - Elsevier
The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …