Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …

The overconsumption of highly caloric and palatable foods has caused a surge in obesity
rates in the past half century, thereby posing a healthcare challenge due to the array of …

Neurons in the hypothalamic arcuate nucleus (ARC) that express agouti‐related peptide
(AgRP) govern a critical aspect of survival: the drive to eat. Equally important to survival is …

The lateral septum (LS) is implicated as a hub that regulates a variety of affects, such as
reward, feeding, anxiety, fear, sociability, and memory. However, it remains unclear how the …

The lateral hypothalamic area (LHA) is a subcortical brain region that exerts control over
motivated behavior, feeding, and energy balance across species. Recent single-cell …

Animals continuously weigh hunger and thirst against competing needs, such as social
contact and mating, according to state and opportunity. Yet neuronal mechanisms of sensing …

Our wellness relies on continuous interactions between our brain and body: different organs
relay their current state to the brain and are regulated, in turn, by descending visceromotor …

For survival, it is crucial for eating behaviours to be sequenced through two distinct seeking
and consummatory phases. Heterogeneous lateral hypothalamus (LH) neurons are known …

Due to unique characteristics, umami substances have gained much attention in the food
industry during the past decade as potential replacers to sodium or fat to increase food …

The rewarding taste of food is critical for motivating animals to eat, but whether taste has a
parallel function in promoting meal termination is not well understood. Here, we show that …