Natural antioxidants have received tremendous attention over the last 3 decades. At the
same time, the attitude to free radicals is slowly changing, and their signalling role in …

Alzheimer's disease (AD) is a multifactorial, rapidly progressing neurodegenerative disorder.
As the exact cause of the disease is still unclear, the drug development is very challenging …

Chlorpyrifos (CPF) is an organophosphorus pesticide widely used in agricultural
applications and household environments. 6-Gingerol-rich fraction from Zingiber officinale …

Heavy metals are reported as neurodegenerative disorders progenitor. They play a role in
the precipitation of abnormal β-amyloid protein and hyper-phosphorylated tau, the main …

Fluoride is an element with toxic properties and has been proven to have some adverse
effects on many soft tissues, including brain tissue. This study aims to evaluate the protective …

Fluoride is one of the major toxicants in the environment and is often found in drinking water
at higher concentrations. Living organisms including humans exposed to high fluoride levels …

Taurine is a sulfur-containing, semi-essential amino acid that occurs naturally in the body. It
alternates between inflammation and oxidative stress-mediated injury in various disease …

Fluoride is becoming an ineluctable environmental pollutant and its longterm exposure
would cause fluorosis and irreversible brain damage, but the molecular mechanisms remain …

Fluoride is commonly consider as a “double-edged sword” because low consumption of
fluoride can effectively prevent dental caries, but excessive consumption of fluoride can …

Clinical and experimental data have demonstrated that diabetes is associated with
neurological complications. Protocatechuic acid (PCA) is a phenolic phytochemical widely …