Fluorescent probes for targeting the Golgi apparatus: design strategies and applications

S Xu, KC Yan, ZH Xu, Y Wang, TD James - Chemical Society Reviews, 2024 - pubs.rsc.org
The Golgi apparatus is an essential organelle constructed by the stacking of flattened
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …

Targeting inflammation as cancer therapy

M Wang, S Chen, X He, Y Yuan, X Wei - Journal of hematology & oncology, 2024 - Springer
Inflammation has accompanied human beings since the emergence of wounds and
infections. In the past decades, numerous efforts have been undertaken to explore the …

Lessons from 20 years with COX‐2 inhibitors: Importance of dose–response considerations and fair play in comparative trials

CO Stiller, P Hjemdahl - Journal of internal medicine, 2022 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) inhibit the enzyme cyclooxygenase (COX),
which forms prostaglandins involved in pain and inflammation. COX inhibitors have …

Pathways of colorectal carcinogenesis

LH Nguyen, A Goel, DC Chung - Gastroenterology, 2020 - Elsevier
Colorectal cancer is a heterogeneous disease that develops via stepwise accumulation of
well-characterized genetic and epigenetic alterations. We review the genetic changes …

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

Inflammation and cancer: advances and new agents

SM Crusz, FR Balkwill - Nature reviews Clinical oncology, 2015 - nature.com
Tumour-promoting inflammation is considered one of the enabling characteristics of cancer
development. Chronic inflammatory disease increases the risk of some cancers, and strong …

Gut microbiota, inflammation, and colorectal cancer

CA Brennan, WS Garrett - Annual review of microbiology, 2016 - annualreviews.org
Colorectal cancer is the second-leading cause of cancer-related deaths in the United States
and fourth-leading cause of cancer-related deaths worldwide. While cancer is largely …

The mechanism of Bacteroides fragilis toxin contributes to colon cancer formation

WT Cheng, HK Kantilal… - The Malaysian journal of …, 2020 - pmc.ncbi.nlm.nih.gov
The Bacteroides fragilis (B. fragilis) produce biofilm for colonisation in the intestinal tract can
cause a series of inflammatory reactions due to B. fragilis toxin (BFT) which can lead to …

[HTML][HTML] Amelioration of oxidative stress, inflammation and tumor promotion by Tin oxide-Sodium alginate-Polyethylene glycol-Allyl isothiocyanate nanocomposites on …

W Wei, R Li, Q Liu, VD Seshadri… - Arabian Journal of …, 2021 - Elsevier
Background Colorectal cancer (CRC) is a frequently diagnosed cancer that primarily affects
the digestive system and an imperative cause of mortalities worldwide. Objective In this …

[HTML][HTML] NSAIDs and cancer resolution: new paradigms beyond cyclooxygenase

OR Kolawole, K Kashfi - International journal of molecular sciences, 2022 - mdpi.com
Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …