As a progressive, irreversible neurodegenerative disease, Alzheimer's disease (AD)
continues to be a serious public health problem worldwide. Currently, the most available …

Alzheimer's disease (AD) is a progressive and fatal neurodegenerative condition and the
most prevalent cause of dementia. This disease is characterized by progressive cognitive …

Chickpea pod borer, Helicoverpa armigera, displays resistance to chemical insecticides and
transgenics. The potential nontransformative RNAi approach of specific gene silencing by …

Most of the cell's chemical reactions and structural components are facilitated by proteins.
But proteins are highly dynamic molecules, where numerous modifications or changes in the …

The blood–brain barrier (BBB) plays an irreplaceable role in protecting the central nervous
system (CNS) from bloodborne pathogens. However, the BBB complicates the treatment of …

Nanoparticles (NPs) based therapies for Alzheimer's disease (AD) attract interest due to
their ability to pass across or bypass the blood‐brain barrier. Chitosan (CS) NPs or …

The aberrant aggregation of amyloid-β (Aβ) peptides in the brain has been recognized as
the major hallmark of Alzheimer's disease (AD). Thus, the inhibition and dissociation of Aβ …

In the current study, we first established that chitosan oligosaccharides (COS) have
significant anti-fibrillogenic and fibril-destabilising effects on bovine insulin in vitro that …

Introduction Protein aggregation and deposition of uniformly arranged amyloid fibrils in the
form of plaques or amorphous aggregates is characteristic of amyloid diseases. The …

Neurological disorders have become severe and dreadful issues around the globe that are
rarely directly mediated because of the blood-brain barrier (BBB). Despite the various …