Neutrophils are the most abundant immune cell type in the blood and constitute the first line
of defense against invading pathogens. Despite their important role in many diseases, they …

The neutrophil is a key player in immunity, and its activities are essential for the resolution of
infections. Neutrophil-pathogen interactions usually trigger a large arsenal of antimicrobial …

IL-33, a nuclear alarmin released during cell death, exerts context-specific effects on
adaptive and innate immune cells, eliciting potent inflammatory responses. We screened …

Several of the most significant bacterial pathogens in humans, including Streptococcus
pyogenes, express surface proteins that bind IgG antibodies via their fragment crystallizable …

Neutrophils constitute a critical part of innate immunity and are well known for their ability to
phagocytose and kill invading microorganisms. The microbicidal processes employed by …

M and M-like proteins are major virulence factors of the widespread and potentially deadly
bacterial pathogen Streptococcus pyogenes. These proteins confer resistance against …

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to
manipulate the immune system through various mechanisms. GAS'M protein constitutes a …

This study aims to investigate the roles of lncRNA ANRIL in epithelial-mesenchymal
transition (EMT) by regulating the ATM-E2F1 signaling pathway in pancreatic cancer (PC) …

Background Perioperative infections, particularly surgical site infections pose significant
morbidity and mortality. Phagocytosis is a critical step for microbial eradication. We …

Hypersegmentation of nuclei is considered a distinct characteristic of the antitumoral
phenotype of neutrophils. Retinoic acid, a metabolite of retinol, reorganizes and induces …