Targeting galectin-driven regulatory circuits in cancer and fibrosis
Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a
broad range of physiological and pathological processes. As a group, these proteins use …
broad range of physiological and pathological processes. As a group, these proteins use …
Overcoming obstacles in the tumor microenvironment: Recent advancements in nanoparticle delivery for cancer theranostics
Despite rapid advancements in the field of nanotechnology, there is mounting frustration in
the scientific community regarding the translational impact of nanomedicine. Modest …
the scientific community regarding the translational impact of nanomedicine. Modest …
[HTML][HTML] Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world
In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …
to have a tremendous impact to offer better health facilities. In this context, medical …
Biomimetic solid-state nanochannels for chemical and biological sensing applications
Biomimetic solid-state nanochannels enable new modalities for biosensing. In the last
decade, these nanofluidic architectures have been widely studied due to their rapid and …
decade, these nanofluidic architectures have been widely studied due to their rapid and …
Particle targeting in complex biological media
Q Dai, N Bertleff‐Zieschang… - Advanced …, 2018 - Wiley Online Library
Over the past few decades, nanoengineered particles have gained increasing interest for
applications in the biomedical realm, including diagnosis, imaging, and therapy. When …
applications in the biomedical realm, including diagnosis, imaging, and therapy. When …
The role of galectin-1 in cancer progression, and synthetic multivalent systems for the study of galectin-1
JM Cousin, MJ Cloninger - International journal of molecular sciences, 2016 - mdpi.com
This review discusses the role of galectin-1 in the tumor microenvironment. First, the
structure and function of galectin-1 are discussed. Galectin-1, a member of the galectin …
structure and function of galectin-1 are discussed. Galectin-1, a member of the galectin …
Chagas disease diagnostic applications: present knowledge and future steps
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …
illness of major significance throughout Latin America and an emergent threat to global …
Recent advances on smart glycoconjugate vaccines in infections and cancer
M Anderluh, F Berti, A Bzducha‐Wróbel… - The FEBS …, 2022 - Wiley Online Library
Vaccination is one of the greatest achievements in biomedical research preventing death
and morbidity in many infectious diseases through the induction of pathogen‐specific …
and morbidity in many infectious diseases through the induction of pathogen‐specific …
Plant Lectins Targeting O-Glycans at the Cell Surface as Tools for Cancer Diagnosis, Prognosis and Therapy
G Poiroux, A Barre, EJM Van Damme… - International journal of …, 2017 - mdpi.com
Aberrant O-glycans expressed at the surface of cancer cells consist of membrane-tethered
glycoproteins (T and Tn antigens) and glycolipids (Lewis a, Lewis x and Forssman …
glycoproteins (T and Tn antigens) and glycolipids (Lewis a, Lewis x and Forssman …
Carrier diversity and chemical ligations in the toolbox for designing tumor-associated carbohydrate antigens (TACAs) as synthetic vaccine candidates
This review highlights the recent development in the use of carriers of increasing simplicities
and versatile chemical ligation processes leading to synthetic vaccine candidates against …
and versatile chemical ligation processes leading to synthetic vaccine candidates against …