RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …

The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …

In eukaryotes, DNA is packed inside the cell nucleus in the form of chromatin, which consists
of DNA, proteins such as histones, and RNA. Euchromatin, which is permissive for …

Similar to epigenetic DNA and histone modifications, epitranscriptomic modifications (RNA
modifications) have emerged as crucial regulators in temporal and spatial gene expression …

During the maternal-to-zygotic transition (MZT), multiple mechanisms precisely control
massive decay of maternal mRNAs. N 6-methyladenosine (m 6 A) is known to regulate …

Transcriptome-wide identification of RNA-binding proteins (RBPs) is a prerequisite for
understanding the posttranscriptional gene regulation networks. However, proteomic …

Functional studies of long noncoding RNAs (lncRNAs) have been hindered by the lack of
methods to assess their evolution. Here we present lncRNA Homology Explorer (lncHOME) …

RNA-binding proteins (RBPs) play a crucial role in regulating RNA function and fate.
However, the full complement of RBPs has only recently begun to be uncovered through …

Hypoxia inhibits the tricarboxylic acid (TCA) cycle and leaves glycolysis as the primary
metabolic pathway responsible for converting glucose into usable energy. However, the …

Background Early embryonic developmental programs are guided by the coordinated
interplay between maternally inherited and zygotically manufactured RNAs and proteins …