The role of serotonin in drug use and addiction
CP Müller, JR Homberg - Behavioural brain research, 2015 - Elsevier
The use of psychoactive drugs is a wide spread behaviour in human societies. The
systematic use of a drug requires the establishment of different drug use-associated …
systematic use of a drug requires the establishment of different drug use-associated …
[HTML][HTML] Serotonin receptors in depression: from A to B
The role of serotonin in major depressive disorder (MDD) is the focus of accumulating
clinical and preclinical research. The results of these studies reflect the complexity of …
clinical and preclinical research. The results of these studies reflect the complexity of …
5-HT receptors and reward-related behaviour: a review
Abstract The brain's serotonin (5-HT) system is key in the regulation of reward-related
behaviours, from eating and drinking to sexual activity. The complexity of studying this …
behaviours, from eating and drinking to sexual activity. The complexity of studying this …
Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction
Cocaine abuse and addiction remain great challenges on the public health agendas in the
US and the world. Increasingly sophisticated perspectives on addiction to cocaine and other …
US and the world. Increasingly sophisticated perspectives on addiction to cocaine and other …
Novel pharmacotherapeutic treatments for cocaine addiction
D Shorter, TR Kosten - BMC medicine, 2011 - Springer
Cocaine is a stimulant that leads to the rapid accumulation of catecholamines and serotonin
in the brain due to prevention of their re-uptake into the neuron that released the …
in the brain due to prevention of their re-uptake into the neuron that released the …
Behavioral evidence for the significance of serotoninergic (5‐HT) receptors in cocaine addiction
Cocaine addiction has somatic, psychological, psychiatric, socio‐economic and legal
implications in the developed world. Presently, there is no medication approved for the …
implications in the developed world. Presently, there is no medication approved for the …
Evaluation of the relationship between anxiety during withdrawal and stress-induced reinstatement of cocaine seeking
S Erb - Progress in Neuro-Psychopharmacology and …, 2010 - Elsevier
The initial termination of cocaine consumption in human addicts is associated with
heightened anxiety states and low levels of craving. Craving, however, tends to increase …
heightened anxiety states and low levels of craving. Craving, however, tends to increase …
Emerging drugs for the treatment of cocaine use disorder: a review of neurobiological targets and pharmacotherapy
D Shorter, CB Domingo, TR Kosten - Expert opinion on emerging …, 2015 - Taylor & Francis
Introduction: Cocaine use is a global public health concern of significant magnitude,
negatively impacting both the individual as well as larger society. Despite numerous trials …
negatively impacting both the individual as well as larger society. Despite numerous trials …
Stimulation of medial prefrontal cortex serotonin 2C (5-HT2C) receptors attenuates cocaine-seeking behavior
NS Pentkowski, FD Duke, SM Weber… - …, 2010 - nature.com
Abstract Serotonin 2C receptor (5-HT 2C R) agonists administered systemically attenuate
both cocaine-primed and cue-elicited reinstatement of extinguished cocaine-seeking …
both cocaine-primed and cue-elicited reinstatement of extinguished cocaine-seeking …
Dopamine D3 and 5-HT1B receptor dysregulation as a result of psychostimulant intake and forced abstinence: Implications for medications development
Addiction to psychostimulants, including cocaine and amphetamine, is associated with
dysregulation of dopamine and serotonin (5-HT) neurotransmitter systems …
dysregulation of dopamine and serotonin (5-HT) neurotransmitter systems …