The lysyl oxidase family comprises five members in mammals, lysyl oxidase (LOX) and four
lysyl oxidase like proteins (LOXL1-4). They are copper amine oxidases with a highly …

Elastic fibres are essential extracellular matrix macromolecules comprising an elastin core
surrounded by a mantle of fibrillin-rich microfibrils. They endow connective tissues such as …

Lysyl oxidase (LO) plays a critical role in the formation and repair of the extracellular matrix
(ECM) by oxidizing lysine residues in elastin and collagen, thereby initiating the formation of …

Elastic fibers are components of the extracellular matrix and confer resilience. Once laid
down, they are thought to remain stable, except in the uterine tract where cycles of active …

Background—The lysyl oxidases are extracellular copper enzymes that initiate the
crosslinking of collagens and elastin, 5 human isoenzymes having been characterized so …

The five genes of the lysyl oxidase family encode enzymes that covalently cross-link
components of the extracellular matrix, such as various types of collagen and elastin, and …

Lysyl oxidase (LOX) family oxidases, LOX and LOXL1-4, oxidize lysine residues in
collagens and elastin, resulting in the covalent crosslinking and stabilization of these …

Elastic fibers provide recoil to tissues that undergo repeated stretch, such as the large
arteries and lung. These large extracellular matrix (ECM) structures contain numerous …

The vertebrate collagen superfamily now includes over 50 collagens and collagen-like
proteins. Here, their different structures are described, as well as their diverse forms of …

We investigated whether the quality of myocardial collagen associates with elevated left-
sided filling pressures in 38 hypertensive patients with stage C chronic heart failure. Filling …