An effective therapeutic strategy to treat tendon or ligament injury continues to be a clinical
challenge due to the limited natural healing capacity of these tissues. Furthermore, the …

Bovine pericardium (BP) has been used as leaflets of prosthetic heart valves. The leaflets
are sutured on metallic stents and can survive 400 million flaps (~ 10-year life span) …

Overuse injuries to dense collagenous tissues are common, but their etiology is poorly
understood. The predominant hypothesis that micro-damage accumulation exceeds the rate …

The transmission of mechanical muscle force to bone for musculoskeletal stability and
movement is one of the most important functions of tendon. The load-bearing tendon core is …

Skeletal muscles are considered to date the best existing actuator in nature thanks to their
hierarchical multiscale fibrous structure capable to enhance their strength and contractile …

Tendon allograft and xenograft processing often involves one or more steps of freezing and
thawing. As failure strength is an important graft consideration, this study aimed to evaluate …

Rodent tendons are widely used to study human pathologies such as tendinopathy and
repair, and to address fundamental physiological questions about development, growth, and …

It is common in biomechanics to use previously frozen tissues, where it is assumed that the
freeze–thaw process does not cause consequential mechanical or structural changes. We …

There is an abrupt increase in the multiscale mechanical properties and load-bearing
capabilities of tendon during development. While prior work has identified numerous …

The present work reports on the multiaxial region and orientation-dependent mechanical
properties of two porcine wrap-around tendons under tensile, compressive and combined …