Nanoparticles for radiation therapy enhancement: the key parameters

P Retif, S Pinel, M Toussaint, C Frochot… - …, 2015 - pmc.ncbi.nlm.nih.gov
This review focuses on the radiosensitization strategies that use high-Z nanoparticles. It
does not establish an exhaustive list of the works in this field but rather propose constructive …

Roadmap to clinical use of gold nanoparticles for radiation sensitization

J Schuemann, R Berbeco, DB Chithrani, SH Cho… - International Journal of …, 2016 - Elsevier
The past decade has seen a dramatic increase in interest in the use of gold nanoparticles
(GNPs) as radiation sensitizers for radiation therapy. This interest was initially driven by their …

Comparing gold nano-particle enhanced radiotherapy with protons, megavoltage photons and kilovoltage photons: a Monte Carlo simulation

Y Lin, SJ McMahon, M Scarpelli… - Physics in Medicine …, 2014 - iopscience.iop.org
Gold nanoparticles (GNPs) have shown potential to be used as a radiosensitizer for
radiation therapy. Despite extensive research activity to study GNP radiosensitization using …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …

Targeted radiotherapy with gold nanoparticles: current status and future perspectives

W Ngwa, R Kumar, S Sridhar, H Korideck… - …, 2014 - Taylor & Francis
Radiation therapy (RT) is the treatment of cancer and other diseases with ionizing radiation.
The ultimate goal of RT is to destroy all the disease cells while sparing healthy tissue …

Standards and methodologies for characterizing radiobiological impact of high-Z nanoparticles

A Subiel, R Ashmore, G Schettino - Theranostics, 2016 - pmc.ncbi.nlm.nih.gov
Research on the application of high-Z nanoparticles (NPs) in cancer treatment and
diagnosis has recently been the subject of growing interest, with much promise being shown …

Dual-energy CT imaging of tumor liposome delivery after gold nanoparticle-augmented radiation therapy

JR Ashton, KD Castle, Y Qi, DG Kirsch, JL West… - …, 2018 - pmc.ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) are emerging as promising agents for both cancer therapy and
computed tomography (CT) imaging. AuNPs absorb x-rays and subsequently release low …

[HTML][HTML] Recent advances in cancer therapy based on dual mode gold nanoparticles

E Spyratou, M Makropoulou, EP Efstathopoulos… - Cancers, 2017 - mdpi.com
Many tumor-targeted strategies have been used worldwide to limit the side effects and
improve the effectiveness of therapies, such as chemotherapy, radiotherapy (RT), etc …

[HTML][HTML] Requirements for designing an effective metallic nanoparticle (NP)-boosted radiation therapy (RT)

I Tremi, E Spyratou, M Souli, EP Efstathopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Recent advances in nanotechnology gave rise to trials with various types
of metallic nanoparticles (NPs) to enhance the radiosensitization of cancer cells while …

Dependence of Monte Carlo microdosimetric computations on the simulation geometry of gold nanoparticles

P Zygmanski, B Liu, P Tsiamas, F Cifter… - Physics in Medicine …, 2013 - iopscience.iop.org
Recently, interactions of x-rays with gold nanoparticles (GNPs) and the resulting dose
enhancement have been studied using several Monte Carlo (MC) codes (Jones et al 2010 …