A wide range of biological activities is exhibited by 1, 3, 4-thiadiazole moiety such as
antidiabetic, anticancer, anti-inflammatory, anticonvulsant, antiviral, antihypertensive, and …

1, 3, 4-thiadiazole is a five-membered aromatic heterocycle containing two nitrogen atoms
and one sulfur atom. As a privileged scaffold, it has its unique chemical properties and …

1, 3, 4-Thiadiazole moiety has various biological activities including anticancer, antidiabetic,
antihypertensive, anti-inflammatory, antiviral, and anti-microbial. Some drugs with …

Herein we describe the synthesis of imidazo [2, 1-b][1, 3, 4] thiadiazoles from carbohydrates
with D-ribo and D-xylo configuration. The antiviral activity of these compounds was tested …

A green and efficient method was developed for the synthesis of 1, 3, 4-thiadiazole based
compounds under microwave (MW) activation. The nucleophile N-(5-amino-1, 3, 4 …

Heterocyclic compounds are the ones that have always remained in the limelight owing to
their superior contributions toward various disciplines such as biology, medicine, material …

This study explores the design, synthesis, and evaluation of a novel series of isobenzofuran-
based imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives, targeting their antimicrobial and …

Natural products play an important role in drug discovery. This work employed a natural
product 1-methylhydantoin as the lead compound to develop novel dual-active drugs. 1 …

The aim of the present study was to investigate the polyphenolic profile and the anti-
inflammatory and anti-nociceptive activities of four traditionally used medicinal plants from …

The syntheses of two macrocycles containing original imidazothiadiazole heterocycles are
presented. The protonation constants of the ligands have been determined by potentiometry …