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Rhinitis 2020: a practice parameter update
This comprehensive practice parameter for allergic rhinitis (AR) and nonallergic rhinitis
(NAR) provides updated guidance on diagnosis, assessment, selection of monotherapy and …
(NAR) provides updated guidance on diagnosis, assessment, selection of monotherapy and …
Capsaicin: current understanding of its mechanisms and therapy of pain and other pre-clinical and clinical uses
In this review, we discuss the importance of capsaicin to the current understanding of
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …
Non‐allergic rhinitis: position paper of the European Academy of Allergy and Clinical Immunology
This EAACI position paper aims at providing a state‐of‐the‐art overview on nonallergic
rhinitis (NAR). A significant number of patients suffering from persistent rhinitis are defined …
rhinitis (NAR). A significant number of patients suffering from persistent rhinitis are defined …
[HTML][HTML] Precision medicine in patients with allergic diseases: airway diseases and atopic dermatitis—PRACTALL document of the European Academy of Allergy and …
In this consensus document we summarize the current knowledge on major asthma, rhinitis,
and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration …
and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration …
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
[HTML][HTML] Impaired barrier function in patients with house dust mite–induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression
Background Tight junction (TJ) defects have recently been associated with asthma and
chronic rhinosinusitis. The expression, function, and regulation of nasal epithelial TJs …
chronic rhinosinusitis. The expression, function, and regulation of nasal epithelial TJs …
[HTML][HTML] Histamine and T helper cytokine–driven epithelial barrier dysfunction in allergic rhinitis
Background Allergic rhinitis (AR) is characterized by mucosal inflammation, driven by
activated immune cells. Mast cells and TH 2 cells might decrease epithelial barrier integrity …
activated immune cells. Mast cells and TH 2 cells might decrease epithelial barrier integrity …
Endotypes of allergic diseases and asthma: an important step in building blocks for the future of precision medicine
abstract Discoveries from basic science research in the last decade have brought significant
progress in knowledge of pathophysiologic processes of allergic diseases, with a …
progress in knowledge of pathophysiologic processes of allergic diseases, with a …
Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report
Rhinitis is an umbrella term that encompasses many different subtypes, several of which still
elude complete characterization. The concept of phenoty**, being the definition of disease …
elude complete characterization. The concept of phenoty**, being the definition of disease …
Endotype-driven treatment in chronic upper airway diseases
Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease.
Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30 …
Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30 …