Metabolic engineering advances and prospects for amino acid production

VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …

[HTML][HTML] Archaea biotechnology

K Pfeifer, İ Ergal, M Koller, M Basen, B Schuster… - Biotechnology …, 2021 - Elsevier
Archaea are a domain of prokaryotic organisms with intriguing physiological characteristics
and ecological importance. In Microbial Biotechnology, archaea are historically …

Ectoine hyperproduction by engineered Halomonas bluephagenesis

Q Hu, S Sun, Z Zhang, W Liu, X Yi, H He… - Metabolic …, 2024 - Elsevier
Ectoine, a crucial osmoprotectant for salt adaptation in halophiles, has gained growing
interest in cosmetics and medical industries. However, its production remains challenged by …

Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being

S Wolf, J Becker, Y Tsuge, H Kawaguchi… - Essays in …, 2021 - portlandpress.com
The soil microbe Corynebacterium glutamicum is a leading workhorse in industrial
biotechnology and has become famous for its power to synthetise amino acids and a range …

Rational flux-tuning of Halomonas bluephagenesis for co-production of bioplastic PHB and ectoine

H Ma, Y Zhao, W Huang, L Zhang, F Wu, J Ye… - Nature …, 2020 - nature.com
Ectoine, a compatible solute synthesized by many halophiles for hypersalinity resistance,
has been successfully produced by metabolically engineered Halomonas bluephagenesis …

Recent advances in production and applications of ectoine, a compatible solute of industrial relevance

P Kadam, M Khisti, V Ravishankar, V Barvkar… - Bioresource …, 2024 - Elsevier
Extremophilic bacteria growing in saline ecosystems are potential producers of
biotechnologically important products including compatible solutes. Ectoine/hydroxyectoine …

[HTML][HTML] Stressed out: Bacterial response to high salinity using compatible solute biosynthesis and uptake systems, lessons from Vibrionaceae

GJ Gregory, EF Boyd - Computational and structural biotechnology journal, 2021 - Elsevier
Bacteria have evolved mechanisms that allow them to adapt to changes in osmolarity and
some species have adapted to live optimally in high salinity environments such as in the …

[HTML][HTML] Microbial production of extremolytes—high-value active ingredients for nutrition, health care, and well-being

J Becker, C Wittmann - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Extremolytes protect extremophilic microbes from environmental stress.•They
enable multiple applications in cosmetics, food, and health industry.•Ectoine is the industrial …

PCR enhancers: Types, mechanisms, and applications in long-range PCR

H Karunanathie, PS Kee, SF Ng, MA Kennedy… - Biochimie, 2022 - Elsevier
Polymerase chain reaction is an important tool in molecular biology. Although the principles
of the technique are relatively simple, amplifying complex or long DNA segments can be …

[HTML][HTML] The osmolyte-producing endophyte Streptomyces albidoflavus OsiLf-2 induces drought and salt tolerance in rice via a multi-level mechanism

S Niu, Y Gao, H Zi, Y Liu, X Liu, X **ong, Q Yao, Z Qin… - The Crop Journal, 2022 - Elsevier
Drought and salinity are major environmental stresses that impair crop growth and
productivity worldwide. Improving drought and salt tolerance of crops with microbial …