[HTML][HTML] Breast cancer genomics and immuno-oncological markers to guide immune therapies

D Hammerl, M Smid, AM Timmermans, S Sleijfer… - Seminars in cancer …, 2018 - Elsevier
There is an increasing awareness of the importance of tumor–immune cell interactions to the
evolution and therapy responses of breast cancer (BC). Not surprisingly, numerous studies …

The human cytomegalovirus, from oncomodulation to oncogenesis

G Herbein - Viruses, 2018 - mdpi.com
Besides its well-described impact in immunosuppressed patients, the role of human
cytomegalovirus (HCMV) in the pathogenesis of cancer has been more recently …

Cytomegalovirus subverts macrophage identity

S Baasch, P Giansanti, J Kolter, A Riedl, AJ Forde… - Cell, 2021 - cell.com
Cytomegaloviruses (CMVs) have co-evolved with their mammalian hosts for millions of
years, leading to remarkable host specificity and high infection prevalence. Macrophages …

Survival in patients with glioblastoma receiving valganciclovir

C Söderberg-Nauclér, A Rahbar… - New England Journal …, 2013 - Mass Medical Soc
Survival in Patients with Glioblastoma Receiving Valganciclovir | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Polyploid giant cancer cells, EZH2 and Myc upregulation in mammary epithelial cells infected with high-risk human cytomegalovirus

Z Nehme, S Pasquereau, SH Ahmad, R El Baba… - …, 2022 - thelancet.com
Background Human cytomegalovirus (HCMV) infection has been actively implicated in
complex neoplastic processes. Beyond oncomodulation, the molecular mechanisms that …

Immune landscape of CMV infection in cancer patients: from “canonical” diseases toward virus-elicited oncomodulation

R El Baba, G Herbein - Frontiers in immunology, 2021 - frontiersin.org
Human Cytomegalovirus (HCMV) is an immensely pervasive herpesvirus, persistently
infecting high percentages of the world population. Despite the apparent robust host …

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications

CS Nauclér, J Geisler, K Vetvik - Oncotarget, 2019 - pmc.ncbi.nlm.nih.gov
It is well-established that infections with viruses harboring oncogenic potential increase the
cancer risk. Virus induced oncogenic processes are influenced by a complex and unique …

Cytomegalovirus and Epstein-Barr virus in breast cancer

AK Richardson, MJ Currie, BA Robinson, H Morrin… - PloS one, 2015 - journals.plos.org
Findings of polymerase chain reaction (PCR) studies of cytomegalovirus (CMV) and Epstein-
Barr virus (EBV) and breast cancer vary, making it difficult to determine whether either, both …

Tumors and cytomegalovirus: An intimate interplay

G Herbein - Viruses, 2022 - mdpi.com
Human cytomegalovirus (HCMV) is a herpesvirus that alternates lytic and latent infection,
infecting between 40 and 95% of the population worldwide, usually without symptoms …

Functional profile of human cytomegalovirus genes and their associated diseases: a review

L Ye, Y Qian, W Yu, G Guo, H Wang, X Xue - Frontiers in microbiology, 2020 - frontiersin.org
The human cytomegalovirus (HCMV), whose genome is 235±1.9 kbp long, is a common
herpesvirus. However, the functions of many of its genes are still unknown. HCMV is closely …