Engineering microneedle patches for improved penetration: analysis, skin models and factors affecting needle insertion
Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …
of active compounds into the skin. To serve as a substitute for common hypodermic needles …
[HTML][HTML] Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
E Larrañeta, REM Lutton, AD Woolfson… - Materials Science and …, 2016 - Elsevier
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
An overview of microneedle applications, materials, and fabrication methods
Microneedle-based microdevices promise to expand the scope for delivery of vaccines and
therapeutic agents through the skin and withdrawing biofluids for point-of-care diagnostics …
therapeutic agents through the skin and withdrawing biofluids for point-of-care diagnostics …
Microneedles for painless transdermal immunotherapeutic applications
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …
the treatment of various diseases. However, owing to the dynamic nature of the immune …
Biodegradable 3D printed polymer microneedles for transdermal drug delivery
Biodegradable polymer microneedle (MN) arrays are an emerging class of transdermal drug
delivery devices that promise a painless and sanitary alternative to syringes; however …
delivery devices that promise a painless and sanitary alternative to syringes; however …
[HTML][HTML] Microneedle-based delivery: An overview of current applications and trends
Microneedle arrays (MNA) are considered as one of the most promising resources to
achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally …
achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally …
Poloxamer hydrogels for biomedical applications
E Russo, C Villa - Pharmaceutics, 2019 - mdpi.com
This review article focuses on thermoresponsive hydrogels consisting of poloxamers which
are of high interest for biomedical application especially in drug delivery for ophthalmic …
are of high interest for biomedical application especially in drug delivery for ophthalmic …
Microneedles for intradermal and transdermal drug delivery
The formidable barrier properties of the uppermost layer of the skin, the stratum corneum,
impose significant limitations for successful systemic delivery of broad range of therapeutic …
impose significant limitations for successful systemic delivery of broad range of therapeutic …
Insulin delivery systems combined with microneedle technology
Diabetes, a metabolic disorder of glucose, is a serious chronic disease and an important
public health problem. Insulin is one of the hormones for modulating blood glucose level …
public health problem. Insulin is one of the hormones for modulating blood glucose level …
Microneedles: Characteristics, materials, production methods and commercial development
Although transdermal drug delivery systems (DDS) offer numerous benefits for patients,
including the avoidance of both gastric irritation and first-pass metabolism effect, as well as …
including the avoidance of both gastric irritation and first-pass metabolism effect, as well as …