Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …
physiology and pathology in living systems, making significant contributions to life science …
Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
Protein assembly by design
Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …
machines and dynamic materials, ranging from protein complexes such as photosystem II …
Click and bioorthogonal chemistry: the future of active targeting of nanoparticles for nanomedicines?
Over the years, click and bioorthogonal reactions have been the subject of considerable
research efforts. These high-performance chemical reactions have been developed to meet …
research efforts. These high-performance chemical reactions have been developed to meet …
Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation
The chemistry of carbohydrates has a history of over 100 years, but simple, stereoselective
and efficient glycosylation methods remain highly needed to facilitate the studies of sugars …
and efficient glycosylation methods remain highly needed to facilitate the studies of sugars …
Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo
Recently, click chemistry has provided important advances in biomedical research fields.
Particularly, copper-free click chemistry including strain-promoted azide–alkyne …
Particularly, copper-free click chemistry including strain-promoted azide–alkyne …
Automated solution-phase multiplicative synthesis of complex glycans up to a 1,080-mer
W Yao, DC **ong, Y Yang, C Geng, Z Cong, F Li… - Nature …, 2022 - nature.com
Carbohydrates play essential roles in nature, such as in cell–cell communication, cell growth
and immunoresponse. However, the synthesis of structurally well-defined carbohydrates …
and immunoresponse. However, the synthesis of structurally well-defined carbohydrates …
Pathological implication of protein post-translational modifications in cancer
S Pan, R Chen - Molecular aspects of medicine, 2022 - Elsevier
Protein post-translational modifications (PTMs) profoundly influence protein functions and
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …
Diversification of glycosyl compounds via glycosyl radicals
Glycosyl radical functionalization is one of the central topics in synthetic carbohydrate
chemistry. Recent advances in metal‐catalyzed cross‐coupling chemistry and …
chemistry. Recent advances in metal‐catalyzed cross‐coupling chemistry and …
Bioactive synthetic polymers
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …
construction and medicine, among many other important applications. Alternatively, natural …