A journey from structure to function of bacterial lipopolysaccharides

F Di Lorenzo, KA Duda, R Lanzetta, A Silipo… - Chemical …, 2021 - ACS Publications
Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

Primary structure of glycans by NMR spectroscopy

C Fontana, G Widmalm - Chemical Reviews, 2023 - ACS Publications
Glycans, carbohydrate molecules in the realm of biology, are present as biomedically
important glycoconjugates and a characteristic aspect is that their structures in many …

Updates to the symbol nomenclature for glycans guidelines

S Neelamegham, K Aoki-Kinoshita, E Bolton… - …, 2019 - academic.oup.com
Abstract The Symbol Nomenclature for Glycans (SNFG) is a community-curated standard for
the depiction of monosaccharides and complex glycans using various colored-coded …

Assembly of bacterial capsular polysaccharides and exopolysaccharides

C Whitfield, SS Wear, C Sande - Annual Review of Microbiology, 2020 - annualreviews.org
Polysaccharides are dominant features of most bacterial surfaces and are displayed in
different formats. Many bacteria produce abundant long-chain capsular polysaccharides …

[HTML][HTML] Liquid-state NMR spectroscopy for complex carbohydrate structural analysis: A hitchhiker's guide

I Speciale, A Notaro, P Garcia-Vello, F Di Lorenzo… - Carbohydrate …, 2022 - Elsevier
Structural determination of carbohydrates is mostly performed by liquid-state NMR, and it is
a demanding task because the NMR signals of these biomolecules explore a rather narrow …

Multifaceted computational modeling in glycoscience

S Perez, O Makshakova - Chemical Reviews, 2022 - ACS Publications
Glycoscience assembles all the scientific disciplines involved in studying various molecules
and macromolecules containing carbohydrates and complex glycans. Such an ensemble …

Creation of a milk oligosaccharide database, MilkOligoDB, reveals common structural motifs and extensive diversity across mammals

SD Durham, Z Wei, DG Lemay, MC Lange, D Barile - Scientific reports, 2023 - nature.com
The carbohydrate fraction of most mammalian milks contains a variety of oligosaccharides
that encompass a range of structures and monosaccharide compositions. Human milk …

Identification of a second glycoform of the clinically prevalent O1 antigen from Klebsiella pneumoniae

SD Kelly, OG Ovchinnikova, F Müller… - Proceedings of the …, 2023 - National Acad Sciences
Carbapenemase and extended β-lactamase-producing Klebsiella pneumoniae isolates
represent a major health threat, stimulating increasing interest in immunotherapeutic …

Lipopolysaccharide O-antigens—bacterial glycans made to measure

C Whitfield, DM Williams, SD Kelly - Journal of Biological Chemistry, 2020 - ASBMB
Lipopolysaccharides are critical components of bacterial outer membranes. The more
conserved lipid A part of the lipopolysaccharide molecule is a major element in the …

[HTML][HTML] Sialic acids and other nonulosonic acids

AL Lewis, X Chen, RL Schnaar… - Essentials of Glycobiology …, 2022 - ncbi.nlm.nih.gov
Sialic acids (Sias) are abundant on vertebrate glycoproteins, glycolipids, and milk
oligosaccharides, as well as on some microbial surface glycans, mediating diverse …