The control of body and organ growth is essential for the development of adults with proper
size and proportions, which is important for survival and reproduction. In animals, adult body …

A pair of Y-organs (YOs) are the molting glands of decapod crustaceans. They synthesize
and secrete steroid molting hormones (ecdysteroids) and their activity is controlled by …

Early transplantation and grafting experiments suggest that body organs follow autonomous
growth programs [1–3], therefore pointing to a need for coordination mechanisms to produce …

How different organs in the body sense growth perturbations in distant tissues to coordinate
their size during development is poorly understood. Here we mutate an invertebrate orphan …

Tissue regeneration is not simply a local repair event occurring in isolation from the distant,
uninjured parts of the body. Rather, evidence indicates that regeneration is a whole-animal …

Endocrine control of molting in decapod crustaceans involves the eyestalk neurosecretory
center (X-organ/sinus gland complex), regenerating limbs, and a pair of Y-organs (YOs), as …

Tumor necrosis factor receptors (TNFRs) control pleiotropic pro-inflammatory functions that
range from apoptosis to cell survival. The ability to trigger a particular function will depend …

Organismal development is a complex process as it requires coordination of many aspects
to grow into fit individuals, such as the control of body size and organ growth. Therefore, the …

In both mammals and insects, steroid hormones play a major role in directing the animal's
progression through developmental stages. To maximize fitness outcomes, steroid hormone …

The developmental transition from juvenile to adult is often accompanied by many systemic
changes in morphology, metabolism, and reproduction. Curiously, both mammalian puberty …