Physical and digital phantoms for 2D and 3D x-ray breast imaging: Review on the state-of-the-art and future prospects

A Sarno, C Valero, RM Tucciariello, N Dukov… - Radiation Physics and …, 2023 - Elsevier
Breast phantoms are a fundamental asset both in routine quality assurance programs and
for comparing scanner performance in 2D and 3D x-ray breast imaging. They also play an …

Performance evaluation of digital breast tomosynthesis systems: comparison of current virtual clinical trial methods

NW Marshall, H Bosmans - Physics in Medicine & Biology, 2022 - iopscience.iop.org
Virtual clinical trials (VCT) have been developed by a number of groups to study breast
imaging applications, with the focus on digital breast tomosynthesis imaging. In this review …

Computational breast anatomy simulation using multi-scale Perlin noise

B Barufaldi, CK Abbey, MA Lago… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
Virtual clinical trials (VCTs) of medical imaging require realistic models of human anatomy.
For VCTs in breast imaging, a multi-scale Perlin noise method is proposed to simulate …

The creation of breast lesion models for mammographic virtual clinical trials: a topical review

A Van Camp, K Houbrechts, L Cockmartin… - Progress in …, 2023 - iopscience.iop.org
Simulated breast lesion models, including microcalcification clusters and masses, have
been used in several studies. Realistic lesion models are required for virtual clinical trials to …

Computer simulations of case difficulty in digital breast tomosynthesis using virtual clinical trials

B Barufaldi, TL Vent, PR Bakic… - Medical Physics, 2022 - Wiley Online Library
Abstract Purpose Virtual clinical trials (VCTs) require computer simulations of representative
patients and images to evaluate and compare changes in performance of imaging …

[HTML][HTML] Simulation of breast lesions based upon fractal Perlin noise

H Tomic, AC Costa, A Bjerkén, MAC Vieira… - Physica Medica, 2023 - Elsevier
Purpose Steadily increasing use of computational/virtual phantoms in medical physics has
motivated expanding development of new simulation methods and data representations for …

Simulation and experimental validation of high-resolution test objects for evaluating a next-generation digital breast tomosynthesis prototype

TL Vent, B Barufaldi… - Medical Imaging 2019 …, 2019 - spiedigitallibrary.org
Star pattern test objects are used to evaluate the high-contrast performance of imaging
systems. These objects were used to investigate alternative scanning geometries for a …

Evaluating attenuation correction strategies in a dedicated, single-gantry breast PET-tomosynthesis scanner

S Krishnamoorthy, T Vent, B Barufaldi… - Physics in Medicine …, 2020 - iopscience.iop.org
We are develo** a dedicated, combined breast positron emission tomography (PET)-
tomosynthesis scanner. Both the PET and digital breast tomosynthesis (DBT) scanners are …

Development and evaluation of a method for tumor growth simulation in virtual clinical trials of breast cancer screening

H Tomic, A Bjerkén, G Hellgren… - Journal of Medical …, 2022 - spiedigitallibrary.org
Purpose: Image-based analysis of breast tumor growth rate may optimize breast cancer
screening and diagnosis by suggesting optimal screening intervals and guide the clinical …

Multiple-reader, multiple-case ROC analysis for determining the limit of calcification detection in tomosynthesis

B Barufaldi, P Bakic… - Medical Imaging 2019 …, 2019 - spiedigitallibrary.org
We have conducted virtual clinical trials (VCTs) of digital breast tomosynthesis (DBT) to
evaluate the parameters that affect detectability of breast lesions. The OpenVCT framework …