Smart nanoparticles for cancer therapy

L Sun, H Liu, Y Ye, Y Lei, R Islam, S Tan… - Signal transduction and …, 2023 - nature.com
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

Recent progress in aptamer discoveries and modifications for therapeutic applications

S Ni, Z Zhuo, Y Pan, Y Yu, F Li, J Liu… - … Applied Materials & …, 2020 - ACS Publications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Therapeutic strategies to overcome cisplatin resistance in ovarian cancer

M Song, M Cui, K Liu - European journal of medicinal chemistry, 2022 - Elsevier
Ovarian cancer (OC) is one of the most common gynecologic tumors worldwide and one
with the highest mortality. Cisplatin (DDP) is the first platinum-based complex approved by …

[HTML][HTML] Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review

S Hossen, MK Hossain, MK Basher, MNH Mia… - Journal of advanced …, 2019 - Elsevier
Nonspecific distribution and uncontrollable release of drugs in conventional drug delivery
systems (CDDSs) have led to the development of smart nanocarrier-based drug delivery …

Recent progress in bioconjugation strategies for liposome-mediated drug delivery

B Almeida, OK Nag, KE Rogers, JB Delehanty - Molecules, 2020 - mdpi.com
In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …

Aptamer-conjugated nano-liposome for immunogenic chemotherapy with reversal of immunosuppression

M Kim, JS Lee, W Kim, JH Lee, BH Jun, KS Kim… - Journal of Controlled …, 2022 - Elsevier
Cancer cells have various immune evasion mechanisms that resist the immune cells by
reprogramming the tumor microenvironment (TME), such as programmed death-ligand 1 …

A review on polymer and lipid-based nanocarriers and its application to nano-pharmaceutical and food-based systems

H Lu, S Zhang, J Wang, Q Chen - Frontiers in nutrition, 2021 - frontiersin.org
Recently, owing to well-controlled release, enhanced distribution and increased
permeability, nanocarriers used for alternative drug and food-delivery strategies have …

Cisplatin in ovarian cancer treatment—known limitations in therapy force new solutions

A Zoń, I Bednarek - International journal of molecular sciences, 2023 - mdpi.com
Cisplatin is one of the most commonly used anticancer drugs worldwide. It is mainly used in
the treatment of ovarian cancer, but also used in testicular, bladder and lung cancers. The …

[HTML][HTML] Current status of sorafenib nanoparticle delivery systems in the treatment of hepatocellular carcinoma

FH Kong, QF Ye, XY Miao, X Liu, SQ Huang, L **ong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the
leading causes of cancer-related death worldwide. Advanced HCC displays strong …