Objectives In recent years,'deaths of despair'due to drugs, alcohol and suicide have
contributed to rising mid-life mortality in the USA. We examine whether despair-related …

Opiates, such as morphine, and synthetic opioids, such as fentanyl, constitute a class of
drugs acting on opioid receptors which have been used therapeutically and recreationally …

Objective To determine whether COVID-19 has a significant impact on adequacy of
household income to meet basic needs (primary outcome) and work absence due to …

Objective To examine the trends and characteristics of opioid-related hospital admissions in
England over 10 years, and its burden for the National Health Service and public finances …

The opioid crisis in the United States (US) is one of the most high-profile public health
scandals of the 21st century with millions of people unknowingly becoming dependent on …

Background The UK Government's 'welfare reform'programme included reductions to social
security payments, phased in over the financial years 2011/2012–2015/2016. Previous …

Despite a large body of evidence showing that early-life malnutrition influences adult
outcomes, there is no evidence that early-life starvation causes use of opioids. Studying the …

Background Mortality rates, and related indicators such as life expectancy, are important
markers of the overall health of a population. This report summarises the nature and causes …

This paper studies the impact of austerity measures introduced by the UK government after
2010 on life expectancy and mortality. We combine administrative data sources to create a …

Suicide is the leading cause of unnatural death among people with schizophrenia.
Substance use is a highly prevalent comorbid feature of schizophrenia and a modifiable risk …