[HTML][HTML] Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer

A Amatu, A Sartore-Bianchi, K Bencardino… - Annals of …, 2019‏ - Elsevier
The tropomyosin receptor kinase (TRK) family of receptor tyrosine kinases are encoded by
NTRK genes and have a role in the development and normal functioning of the nervous …

Targeting neurotrophins to specific populations of neurons: NGF, BDNF, and NT-3 and their relevance for treatment of spinal cord injury

KM Keefe, IS Sheikh, GM Smith - International journal of molecular …, 2017‏ - mdpi.com
Neurotrophins are a family of proteins that regulate neuronal survival, synaptic function, and
neurotransmitter release, and elicit the plasticity and growth of axons within the adult central …

The molecular basis of retinal ganglion cell death in glaucoma

M Almasieh, AM Wilson, B Morquette… - Progress in retinal and …, 2012‏ - Elsevier
Glaucoma is a group of diseases characterized by progressive optic nerve degeneration that
results in visual field loss and irreversible blindness. A crucial element in the …

Neuronal plasticity and neurotrophic factors in drug responses

E Castrén, H Antila - Molecular psychiatry, 2017‏ - nature.com
Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other
members of the neurotrophin family, are central mediators of the activity-dependent plasticity …

Neurotrophic factors: an overview

SD Skaper - Neurotrophic Factors: Methods and Protocols, 2018‏ - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …

[HTML][HTML] The functional organization of cutaneous low-threshold mechanosensory neurons

L Li, M Rutlin, VE Abraira, C Cassidy, L Kus, S Gong… - Cell, 2011‏ - cell.com
Innocuous touch of the skin is detected by distinct populations of neurons, the low-threshold
mechanoreceptors (LTMRs), which are classified as Aβ-, Aδ-, and C-LTMRs. Here, we report …

Postsynaptic BDNF‐TrkB signaling in synapse maturation, plasticity, and disease

A Yoshii, M Constantine‐Paton - Developmental neurobiology, 2010‏ - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is a prototypic neurotrophin that regulates diverse
developmental events from the selection of neural progenitors to the terminal dendritic …

Antidiabetic effect of brain‐derived neurotrophic factor and its association with inflammation in type 2 diabetes mellitus

C Eyileten, A Kaplon-Cieslicka… - Journal of diabetes …, 2017‏ - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is a neurotrophin, which plays an important role in
the central nervous system, and systemic or peripheral inflammatory conditions, such as …

The neurotrophin family of neurotrophic factors: an overview

SD Skaper - Neurotrophic factors: Methods and protocols, 2012‏ - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …

The Trk family of neurotrophin receptors

M Barbacid - Journal of neurobiology, 1994‏ - Wiley Online Library
Accumulating evidence indicates that the Trk family of tyrosine protein kinase receptors, Trk
(also known as TrkA), TrkB, and TrkC, are responsible for mediating the trophic effects of the …