Towards consistency in pediatric brain tumor measurements: Challenges, solutions, and the role of artificial intelligence-based segmentation

AM Familiar, A Fathi Kazerooni, A Vossough… - Neuro …, 2024 - academic.oup.com
MR imaging is central to the assessment of tumor burden and changes over time in neuro-
oncology. Several response assessment guidelines have been set forth by the Response …

Novel imaging approaches for glioma classification in the Era of the World Health Organization 2021 update: A sco** review

V Richter, U Ernemann, B Bender - Cancers, 2024 - mdpi.com
Simple Summary The 2021 WHO classification of central nervous system (CNS) tumors is
challenging for neuroradiologists due to the central role of the molecular profile of tumors …

Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma

A Fathi Kazerooni, A Kraya, KS Rathi, MC Kim… - Nature …, 2025 - nature.com
Pediatric low-grade gliomas (pLGGs) exhibit heterogeneous prognoses and variable
responses to treatment, leading to tumor progression and adverse outcomes in cases where …

Stepwise transfer learning for expert-level pediatric brain tumor MRI segmentation in a limited data scenario

A Boyd, Z Ye, SP Prabhu, MC Tjong, Y Zha… - Radiology: Artificial …, 2024 - pubs.rsna.org
Purpose To develop, externally test, and evaluate clinical acceptability of a deep learning
pediatric brain tumor segmentation model using stepwise transfer learning. Materials and …

Tumor location-weighted mri-report contrastive learning: A framework for improving the explainability of pediatric brain tumor diagnosis

S Ketabi, MW Wagner, C Hawkins, U Tabori… - arxiv preprint arxiv …, 2024 - arxiv.org
Despite the promising performance of convolutional neural networks (CNNs) in brain tumor
diagnosis from magnetic resonance imaging (MRI), their integration into the clinical workflow …

Beyond hand-crafted features for pretherapeutic molecular status identification of pediatric low-grade gliomas

K Kudus, MW Wagner, K Namdar, J Bennett… - Scientific Reports, 2024 - nature.com
The use of targeted agents in the treatment of pediatric low-grade gliomas (pLGGs) relies on
the determination of molecular status. It has been shown that genetic alterations in pLGG …

Improving Deep Learning Models for Pediatric Low-Grade Glioma Tumours Molecular Subtype Identification Using MRI-based 3D Probability Distributions of Tumour …

K Namdar, MW Wagner, K Kudus… - Canadian …, 2024 - journals.sagepub.com
Purpose: Pediatric low-grade gliomas (pLGG) are the most common brain tumour in
children, and the molecular diagnosis of pLGG enables targeted treatment. We use MRI …

Generating 3D brain tumor regions in MRI using vector-quantization Generative Adversarial Networks

M Zhou, MW Wagner, U Tabori, C Hawkins… - Computers in Biology …, 2025 - Elsevier
Medical image analysis has significantly benefited from advancements in deep learning,
particularly in the application of Generative Adversarial Networks (GANs) for generating …

A review of deep learning for brain tumor analysis in MRI

FJ Dorfner, JB Patel, J Kalpathy-Cramer… - NPJ Precision …, 2025 - nature.com
Recent progress in deep learning (DL) is producing a new generation of tools across
numerous clinical applications. Within the analysis of brain tumors in magnetic resonance …

Applications of machine learning to MR imaging of pediatric low-grade gliomas

K Kudus, M Wagner, BB Ertl-Wagner, F Khalvati - Child's Nervous System, 2024 - Springer
Introduction Machine learning (ML) shows promise for the automation of routine tasks
related to the treatment of pediatric low-grade gliomas (pLGG) such as tumor grading …