Biologically active quinoline and quinazoline alkaloids part I

XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

Secondary metabolites from Rubiaceae species

D Martins, CV Nunez - Molecules, 2015 - mdpi.com
This study describes some characteristics of the Rubiaceae family pertaining to the
occurrence and distribution of secondary metabolites in the main genera of this family. It …

Quinoline, quinazoline and acridone alkaloids

JP Michael - Natural product reports, 2007 - pubs.rsc.org
Covering: July 2004 to June 2005. Previous review: Nat. Prod. Rep., 2005, 22, 627 This
review covers the isolation, structure determination, synthesis and biological activity of …

Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host

JD Maya, BK Cassels, P Iturriaga-Vásquez… - … and Physiology Part A …, 2007 - Elsevier
Current knowledge of the biochemistry of Trypanosoma cruzi has led to the development of
new drugs and the understanding of their mode of action. Some trypanocidal drugs such as …

Design, synthesis, and antifungal evaluation of novel quinoline derivatives inspired from natural quinine alkaloids

GZ Yang, JK Zhu, XD Yin, YF Yan… - Journal of agricultural …, 2019 - ACS Publications
Inspired by quinine and its analogues, we designed, synthesized, and evaluated two series
of quinoline small molecular compounds (a and 2a) and six series of quinoline derivatives …

Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis

LP Kvist, SB Christensen, HB Rasmussen… - Journal of …, 2006 - Elsevier
Households in eleven geographically and ethnically distinct areas in Loreto, Peru, were
interviewed about their knowledge and use of plants, for the treatment of malaria and …

Phylogeny Predicts the Quantity of Antimalarial Alkaloids within the Iconic Yellow Cinchona Bark (Rubiaceae: Cinchona calisaya)

C Maldonado, CJ Barnes, C Cornett… - Frontiers in Plant …, 2017 - frontiersin.org
Considerable inter-and intraspecific variation with respect to the quantity and composition of
plant natural products exists. The processes that drive this variation remain largely unknown …

[PDF][PDF] Chemistry and biology of Cinchona alkaloids

KM Kacprzak - Natural Products, 2013 - academia.edu
Cinchona alkaloids comprising quinine, quinidine, cinchonidine, and cinchonine as the
major members constitute a unique class of quinoline alkaloids with tremendous impact on …

Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

V Rosenkranz, M Wink - Molecules, 2008 - mdpi.com
The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55
alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and …

Indole Alkaloids from Geissospermum reticulatum

M Reina, W Ruiz-Mesia… - Journal of Natural …, 2012 - ACS Publications
Ten indole alkaloids were isolated from Geissospermum reticulatum, seven (1–7) from the
leaves and three (8–10) from the bark. Seven were aspidospermatan-type alkaloids (1–3, 5 …