Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Depression in neurodegenerative diseases: Common mechanisms and current treatment options

CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Current and possible future therapeutic options for Huntington's disease

MW Ferguson, CJ Kennedy… - Journal of central …, 2022 - journals.sagepub.com
Huntington's disease (HD) is an autosomal neurodegenerative disease that is characterized
by an excessive number of CAG trinucleotide repeats within the huntingtin gene (HTT). HD …

Where in the brain is depression?

M Pandya, M Altinay, DA Malone, A Anand - Current psychiatry reports, 2012 - Springer
Major depressive disorder is a serious medical illness which is responsible for considerable
morbidity and disability. Despite decades of research, the neural basis for depression is still …

Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY)

E van Duijn, D Craufurd, AAM Hubers… - Journal of Neurology …, 2014 - jnnp.bmj.com
Background The majority of Huntington's disease (HD) mutation carriers experience some
psychopathology during their lifetime, varying from irritability to psychosis, but prevalences …

Huntington disease: pathogenesis and treatment

P Dayalu, RL Albin - Neurologic clinics, 2015 - neurologic.theclinics.com
Huntington disease (HD) is an autosomal dominant inherited neurodegenerative disease
characterized by progressive motor, behavioral, and cognitive decline, resulting in death …

Neuroinflammation, neurodegeneration, and depression

LL Hurley, Y Tizabi - Neurotoxicity research, 2013 - Springer
Neurodegeneration and depression are two common co-morbid conditions, particularly
within the aging population. Research has linked neuroinflammation as a major contributing …

Neurological diseases and pain

D Borsook - Brain, 2012 - academic.oup.com
Chronic pain is a frequent component of many neurological disorders, affecting 20–40% of
patients for many primary neurological diseases. These diseases result from a wide range of …

Huntington's disease—update on treatments

KJ Wyant, AJ Ridder, P Dayalu - Current neurology and neuroscience …, 2017 - Springer
Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disease
characterized by progressive motor, behavioral, and cognitive decline, ending in death …

Huntington's disease

MJU Novak, SJ Tabrizi - Bmj, 2010 - bmj.com
Huntington's disease is a devastating inherited neurodegenerative disease characterised by
progressive motor, cognitive, and psychiatric symptoms. Patients may present with any of …