Recognition of the natural abundance and functional importance of intrinsically disordered
proteins (IDPs), and protein hybrids that contain both intrinsically disordered protein regions …

Abstract Arginine shows Jekyll and Hyde behavior in several respects. It participates in
protein folding via ionic and H-bonds and cation-pi interactions; the charge and …

Protein intrinsic disorder is found in all kingdoms of life and is known to underpin numerous
physiological and pathological processes. Computational methods play an important role in …

INTRODUCTION Temperature is crucially important to life. Small temperature changes can
differentiate optimal and lethal growth conditions of living organisms. Because of the higher …

Proteins are the major component of the living cell. They play crucial roles in the
maintenance of life, and their dysfunctions are known to cause different pathologies. One of …

At the turn of the twenty-first century, fundamental changes took place in the understanding
of the structure and function of proteins and then in the appreciation of the intracellular …

It's widely appreciated that liquid–liquid phase separation (LLPS) underlies the formation of
membraneless organelles, which function to concentrate proteins and nucleic acids. In the …

Research of a past decade and a half leaves no doubt that complete understanding of
protein functionality requires close consideration of the fact that many functional proteins do …

Despite the wealth of knowledge gained about intrinsically disordered proteins (IDPs) since
their discovery, there are several aspects that remain unexplored and, hence, poorly …

Intrinsically disordered proteins and intrinsically disordered protein regions are highly
abundant in nature. However, the quantitative and qualitative measures of protein intrinsic …