We have prepared this document,“Sublingual Immunotherapy: World Allergy Organization
Position Paper 2013 Update”, according to the evidence-based criteria, revising and …

Abstract The International Conference on Harmonisation has agreed upon the structure and
content of the Medical Dictionary for Regulatory Activities (MedDRA) version 2.0 which …

Drug survival reflects a drug's effectiveness, safety, and tolerability. We assessed the drug
survival of biologics used to treat psoriasis in a prospective national pharmacovigilance …

Quantitative methods are increasingly used to analyse spontaneous reports. We describe
the core concepts behind the most common methods, the proportional reporting ratio (PRR) …

Signal‐detection algorithms (SDAs) are recognized as vital tools in pharmacovigilance.
However, their performance characteristics are generally unknown. By leveraging a unique …

Robust tools for monitoring the safety of marketed therapeutic products are of paramount
importance to public health. In recent years, innovative statistical approaches have been …

Over a period of 5 years, the Innovative Medicines Initiative PROTECT (
Pharmacoepidemiological Research on Outcomes of Therapeutics by a European …

Automated approaches to measuring semantic similarity and relatedness can provide
necessary semantic context information for information retrieval applications and a number …

Sublingual immunotherapy (SLIT) is increasingly used worldwide. Despite its safety being
well ascertained, there is no universally accepted system to grade and classify its adverse …

Introduction Anti-TNF therapies represent a breakthrough in the treatment of severe psoriatic
arthritis. However, little is known about long-term drug persistence with these treatments in …