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Retinal neurodegeneration as an early manifestation of diabetic eye disease and potential neuroprotective therapies
Abstract Purpose of Review Diabetic retinopathy (DR) is a major cause of visual impairment
and blindness throughout the world. Microvascular changes have long been regarded …
and blindness throughout the world. Microvascular changes have long been regarded …
Neuroinflammation and oxidative stress act in concert to promote neurodegeneration in the diabetic retina and optic nerve: galectin-3 participation
HR Mendonça, R Carpi-Santos… - Neural regeneration …, 2020 - journals.lww.com
Diabetes is a lifelong disease characterized by glucose metabolic imbalance, in which low
insulin levels or impaired insulin signaling lead to hyperglycemic state. Within 20 years of …
insulin levels or impaired insulin signaling lead to hyperglycemic state. Within 20 years of …
Variation of color discrimination across the life span
GV Paramei, B Oakley - Journal of the Optical Society of America A, 2014 - opg.optica.org
The present study, an extension of Paramei [J. Opt. Soc. Am. A, 29, A290, 2012], provides
normative data on chromatic discrimination, using the Cambridge Colour Test, for normal …
normative data on chromatic discrimination, using the Cambridge Colour Test, for normal …
Pathologic alterations of the outer retina in streptozotocin-induced diabetes
Purpose.: Neurodegeneration as an early event of diabetic retinopathy preceding clinically
detectable vascular alterations is a widely proven issue today. While there is evidence for …
detectable vascular alterations is a widely proven issue today. While there is evidence for …
Color discrimination across four life decades assessed by the Cambridge Colour Test
GV Paramei - Journal of the Optical Society of America A, 2012 - opg.optica.org
Color discrimination was estimated using the Cambridge Colour Test (CCT) in 160 normal
trichromats of four life decades, 20–59 years of age. For each age cohort, medians and …
trichromats of four life decades, 20–59 years of age. For each age cohort, medians and …
A critical review: psychophysical assessments of diabetic retinopathy
XD Chen, TW Gardner - Survey of ophthalmology, 2021 - Elsevier
Diabetic retinal disease remains a leading cause of vision loss despite currently available
screening methods, ocular treatments, and efforts to control metabolic dysfunction. It is now …
screening methods, ocular treatments, and efforts to control metabolic dysfunction. It is now …
Melatonin affects mitochondrial fission/fusion dynamics in the diabetic retina
JYA Chang, F Yu, L Shi, ML Ko… - Journal of diabetes …, 2019 - Wiley Online Library
Mitochondrial fission and fusion are dependent on cellular nutritional states, and
maintaining this dynamics is critical for the health of cells. Starvation triggers mitochondrial …
maintaining this dynamics is critical for the health of cells. Starvation triggers mitochondrial …
[HTML][HTML] Cone photoreceptor irregularity on adaptive optics scanning laser ophthalmoscopy correlates with severity of diabetic retinopathy and macular edema
J Lammer, SG Prager, MC Cheney… - … & visual science, 2016 - tvst.arvojournals.org
Purpose: To determine whether cone density, spacing, or regularity in eyes with and without
diabetes (DM) as assessed by high-resolution adaptive optics scanning laser …
diabetes (DM) as assessed by high-resolution adaptive optics scanning laser …
Color vision impairments in schizophrenia and the role of antipsychotic medication type
Schizophrenia patients (SCZ) demonstrate deficits in many domains of mental functioning,
including visual perception. An issue that has been relatively unexplored, in terms of …
including visual perception. An issue that has been relatively unexplored, in terms of …
Color vision and neuroretinal function in diabetes
BE Wolff, MA Bearse, ME Schneck… - Documenta …, 2015 - Springer
Purpose We investigate how type 2 diabetes (T2DM) and diabetic retinopathy (DR) affect
color vision (CV) and mfERG implicit time (IT), whether CV and IT are correlated, and …
color vision (CV) and mfERG implicit time (IT), whether CV and IT are correlated, and …