Retinal neurodegeneration as an early manifestation of diabetic eye disease and potential neuroprotective therapies

S Zafar, M Sachdeva, BJ Frankfort, R Channa - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR) is a major cause of visual impairment
and blindness throughout the world. Microvascular changes have long been regarded …

Neuroinflammation and oxidative stress act in concert to promote neurodegeneration in the diabetic retina and optic nerve: galectin-3 participation

HR Mendonça, R Carpi-Santos… - Neural regeneration …, 2020 - journals.lww.com
Diabetes is a lifelong disease characterized by glucose metabolic imbalance, in which low
insulin levels or impaired insulin signaling lead to hyperglycemic state. Within 20 years of …

Variation of color discrimination across the life span

GV Paramei, B Oakley - Journal of the Optical Society of America A, 2014 - opg.optica.org
The present study, an extension of Paramei [J. Opt. Soc. Am. A, 29, A290, 2012], provides
normative data on chromatic discrimination, using the Cambridge Colour Test, for normal …

Pathologic alterations of the outer retina in streptozotocin-induced diabetes

A Énzsöly, A Szabó, O Kántor, C Dávid… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: Neurodegeneration as an early event of diabetic retinopathy preceding clinically
detectable vascular alterations is a widely proven issue today. While there is evidence for …

Color discrimination across four life decades assessed by the Cambridge Colour Test

GV Paramei - Journal of the Optical Society of America A, 2012 - opg.optica.org
Color discrimination was estimated using the Cambridge Colour Test (CCT) in 160 normal
trichromats of four life decades, 20–59 years of age. For each age cohort, medians and …

A critical review: psychophysical assessments of diabetic retinopathy

XD Chen, TW Gardner - Survey of ophthalmology, 2021 - Elsevier
Diabetic retinal disease remains a leading cause of vision loss despite currently available
screening methods, ocular treatments, and efforts to control metabolic dysfunction. It is now …

Melatonin affects mitochondrial fission/fusion dynamics in the diabetic retina

JYA Chang, F Yu, L Shi, ML Ko… - Journal of diabetes …, 2019 - Wiley Online Library
Mitochondrial fission and fusion are dependent on cellular nutritional states, and
maintaining this dynamics is critical for the health of cells. Starvation triggers mitochondrial …

[HTML][HTML] Cone photoreceptor irregularity on adaptive optics scanning laser ophthalmoscopy correlates with severity of diabetic retinopathy and macular edema

J Lammer, SG Prager, MC Cheney… - … & visual science, 2016 - tvst.arvojournals.org
Purpose: To determine whether cone density, spacing, or regularity in eyes with and without
diabetes (DM) as assessed by high-resolution adaptive optics scanning laser …

Color vision impairments in schizophrenia and the role of antipsychotic medication type

TMP Fernandes, SM Silverstein, PD Butler, S Kéri… - Schizophrenia …, 2019 - Elsevier
Schizophrenia patients (SCZ) demonstrate deficits in many domains of mental functioning,
including visual perception. An issue that has been relatively unexplored, in terms of …

Color vision and neuroretinal function in diabetes

BE Wolff, MA Bearse, ME Schneck… - Documenta …, 2015 - Springer
Purpose We investigate how type 2 diabetes (T2DM) and diabetic retinopathy (DR) affect
color vision (CV) and mfERG implicit time (IT), whether CV and IT are correlated, and …