Bioactive calcium phosphate materials and applications in bone regeneration

J Jeong, JH Kim, JH Shim, NS Hwang… - Biomaterials …, 2019 - spj.science.org
Background Bone regeneration involves various complex biological processes. Many
experiments have been performed using biomaterials in vivo and in vitro to promote and …

Stem cell-friendly scaffold biomaterials: applications for bone tissue engineering and regenerative medicine

Y Zhang, D Wu, X Zhao, M Pakvasa… - … in bioengineering and …, 2020 - frontiersin.org
Bone is a dynamic organ with high regenerative potential and provides essential biological
functions in the body, such as providing body mobility and protection of internal organs …

Scaffolds for bone-tissue engineering

SS Lee, X Du, I Kim, SJ Ferguson - Matter, 2022 - cell.com
Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …

Biomimetic whitlockite inorganic nanoparticles-mediated in situ remodeling and rapid bone regeneration

HD Kim, HL Jang, HY Ahn, HK Lee, J Park, E Lee… - Biomaterials, 2017 - Elsevier
Bone remodeling process relies on complex signaling pathway between osteoblasts and
osteoclasts and control mechanisms to achieve homeostasis of their growth and …

Synergistic interplay between the two major bone minerals, hydroxyapatite and whitlockite nanoparticles, for osteogenic differentiation of mesenchymal stem cells

H Cheng, R Chabok, X Guan, A Chawla, Y Li… - Acta biomaterialia, 2018 - Elsevier
The inorganic part of human bone is mainly composed of hydroxyapatite (HAP: Ca 10 (PO 4)
6 (OH) 2) and whitlockite (WH: Ca 18 Mg 2 (HPO 4) 2 (PO 4) 12) minerals, where the WH …

Resorbable Mg2+-Containing Phosphates for Bone Tissue Repair

G Kazakova, T Safronova, D Golubchikov, O Shevtsova… - Materials, 2021 - mdpi.com
Materials based on Mg2+-containing phosphates are gaining great relevance in the field of
bone tissue repair via regenerative medicine methods. Magnesium ions, together with …

Remotely controlled self-powering electrical stimulators for osteogenic differentiation using bone inspired bioactive piezoelectric whitlockite nanoparticles

VK Kaliannagounder, NPMJ Raj, AR Unnithan, J Park… - Nano Energy, 2021 - Elsevier
Endogenous electric fields naturally exist in our body and plays a vital role especially in the
development and regeneration of bones. Therefore, piezoelectric bone implants are gaining …

In Vitro and In Vivo Evaluation of Whitlockite Biocompatibility: Comparative Study with Hydroxyapatite and β‐Tricalcium Phosphate

HL Jang, GB Zheng, J Park, HD Kim… - Advanced …, 2016 - Wiley Online Library
Biomimicking ceramics have been developed to induce efficient recovery of damaged hard
tissues. Among them, calcium phosphate‐based bioceramics have been the most widely …

Injectable angiogenic and osteogenic carrageenan nanocomposite hydrogel for bone tissue engineering

R Yegappan, V Selvaprithiviraj, S Amirthalingam… - International journal of …, 2019 - Elsevier
Functional biomaterials that couple angiogenesis and osteogenesis processes are vital for
bone tissue engineering and bone remodeling. Herein we developed an injectable …

Dissolution–precipitation synthesis and thermal stability of magnesium whitlockite

A Kizalaite, V Klimavicius, V Balevicius, G Niaura… - …, 2023 - pubs.rsc.org
Magnesium whitlockite (Mg-WH, Ca18Mg2 (HPO4) 2 (PO4) 12) is a promising candidate for
biomedical application in bone regeneration; however, the fabrication of Mg-WH …