[HTML][HTML] Synthetic biology tools to engineer microbial communities for biotechnology

NS McCarty, R Ledesma-Amaro - Trends in biotechnology, 2019 - cell.com
Microbial consortia have been used in biotechnology processes, including fermentation,
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …

Pathways to cellular supremacy in biocomputing

L Grozinger, M Amos, TE Gorochowski… - Nature …, 2019 - nature.com
Synthetic biology uses living cells as the substrate for performing human-defined
computations. Many current implementations of cellular computing are based on the …

Dynamic cybergenetic control of bacterial co-culture composition via optogenetic feedback

J Gutiérrez Mena, S Kumar, M Khammash - Nature Communications, 2022 - nature.com
Communities of microbes play important roles in natural environments and hold great
potential for deploying division-of-labor strategies in synthetic biology and bioproduction …

The ground state of embryonic stem cell self-renewal

QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble… - nature, 2008 - nature.com
In the three decades since pluripotent mouse embryonic stem (ES) cells were first described,
they have been derived and maintained by using various empirical combinations of feeder …

Tools for engineering coordinated system behaviour in synthetic microbial consortia

N Kylilis, ZA Tuza, GB Stan, KM Polizzi - Nature communications, 2018 - nature.com
Advancing synthetic biology to the multicellular level requires the development of multiple
cell-to-cell communication channels that propagate information with minimal signal …

Quorum sensing in synthetic biology: A review

A Boo, RL Amaro, GB Stan - Current Opinion in Systems Biology, 2021 - Elsevier
In nature, quorum sensing is one of the mechanisms bacterial populations use to
communicate with their own species or across species to coordinate behaviours. For the last …

Cybergenetics: Theory and applications of genetic control systems

MH Khammash - Proceedings of the IEEE, 2022 - ieeexplore.ieee.org
There is no design template more important than DNA. Within the sequences of this
exquisite substance lie the design plans for each of us and for every living organism …

Design and analysis of quorum sensing language “interpreter” ecosystem for microbial community

S Wu, H Zhang, Y Zhou, C Xu, B Yuan, H Wang… - Chemical Engineering …, 2024 - Elsevier
Microbes in diverse natural communities communicate via quorum sensing (QS) signals that
act as microbial languages. QS-based communications have been reconstructed in two …

Noise in biomolecular systems: Modeling, analysis, and control implications

C Briat, M Khammash - Annual Review of Control, Robotics, and …, 2023 - annualreviews.org
While noise is generally associated with uncertainties and often has a negative connotation
in engineering, living organisms have evolved to adapt to (and even exploit) such …

Ratiometric control of cell phenotypes in monostrain microbial consortia

D Salzano, D Fiore… - Journal of the Royal …, 2022 - royalsocietypublishing.org
We address the problem of regulating and kee** at a desired balance the relative
numbers between cells exhibiting a different phenotype within a monostrain microbial …