Fluorescent probes for disease diagnosis

X Wang, Q Ding, RR Groleau, L Wu, Y Mao… - Chemical …, 2024‏ - ACS Publications
The identification and detection of disease-related biomarkers is essential for early clinical
diagnosis, evaluating disease progression, and for the development of therapeutics …

Biosystem‐inspired engineering of nanozymes for biomedical applications

L Zhang, H Wang, X Qu - Advanced Materials, 2024‏ - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …

Nanozymes for nanohealthcare

Y Zhang, G Wei, W Liu, T Li, Y Wang, M Zhou… - Nature Reviews …, 2024‏ - nature.com
Nanozymes, nanomaterial-based artificial enzymes, exhibit potential for emulating the
catalytic functions inherent in enzymes. Nanozymes have advantages such as low cost …

Modified prebiotic-based “shield” armed probiotics with enhanced resistance of gastrointestinal stresses and prolonged intestinal retention for synergistic alleviation of …

A **e, H Ji, Z Liu, Y Wan, X Zhang, H **ong, SP Nie… - ACS …, 2023‏ - ACS Publications
Oral administration of probiotics is a promising method to alleviate inflammatory bowel
diseases (IBDs). However, gastrointestinal environmental sensitivity and inferior intestinal …

Multimodal smart systems reprogramme macrophages and remove urate to treat gouty arthritis

J Xu, M Wu, J Yang, D Zhao, D He, Y Liu, X Yan… - Nature …, 2024‏ - nature.com
Gouty arthritis is a chronic and progressive disease characterized by high urate levels in the
joints and by an inflammatory immune microenvironment. Clinical data indicate that urate …

Nanotechnology in inflammation: Cutting-edge advances in diagnostics, therapeutics and theranostics

Y Liu, Z Lin, Y Wang, L Chen, Y Wang, C Luo - Theranostics, 2024‏ - pmc.ncbi.nlm.nih.gov
Inflammatory dysregulation is intimately associated with the occurrence and progression of
many life-threatening diseases. Accurate detection and timely therapeutic intervention on …

Recent advances on emerging nanomaterials for diagnosis and treatment of inflammatory bowel disease

W Fu, L Xu, Z Chen, L Kan, Y Ma, H Qian… - Journal of Controlled …, 2023‏ - Elsevier
Inflammatory bowel disease (IBD) is a chronic idiopathic inflammatory disorder that affects
the entire gastrointestinal tract and is associated with an increased risk of colorectal cancer …

Ingestible artificial urinary biomarker probes for urine test of gastrointestinal cancer

C Xu, M Xu, Y Hu, J Liu, P Cheng, Z Zeng… - Advanced …, 2024‏ - Wiley Online Library
Although colorectal cancer diagnosed at an early stage shows high curability, methods
simultaneously possessing point‐of‐care testing ability and high sensitivity are limited. Here …

Inhibiting the cGAS-STING pathway in ulcerative colitis with programmable micelles

S Uthaman, S Parvinroo, AP Mathew, X Jia… - ACS …, 2024‏ - ACS Publications
Ulcerative colitis is a chronic condition in which a dysregulated immune response
contributes to the acute intestinal inflammation of the colon. Current clinical therapies often …

Multiscale bioresponses of metal nanoclusters

Y Shi, Z Wu, M Qi, C Liu, W Dong, W Sun… - Advanced …, 2024‏ - Wiley Online Library
Metal nanoclusters (NCs) are well‐recognized novel nano‐agents that hold great promise
for applications in nanomedicine because of their ultrafine size, low toxicity, and high renal …