Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Bronchopulmonary dysplasia (BPD) is the chronic lung disease of prematurity that affects
very preterm infants. Although advances in perinatal care have enabled the survival of …

Objective Preterm brain injury is a major cause of disability in later life, and may result in
motor, cognitive and behavioural impairment for which no treatment is currently available …

Approximately 11.1% of all newborns worldwide are born preterm. Improved neonatal
intensive care significantly increased survival rates over the last decades but failed to …

Preterm birth is an evolving challenge in neonatal health care. Despite declining mortality
rates among extremely premature neonates, morbidity rates remain very high. Currently …

Growing and consistent preclinical evidence, combined with early clinical epidemiological
observations, suggest potentially neurotoxic effects of commonly used anesthetic agents in …

Despite major advances in obstetrics and neonatal intensive care, preterm infants frequently
suffer from neurological impairments in later life. Preterm and also full-term neonates are …

White matter (WM) injury, once known primarily in preterm newborns, is emerging in its non-
focal (diffused), non-necrotic form as a critical component of subtle brain injuries in many …

Neonatal brain injury and associated inflammation is more common in males. There is a well-
recognised difference in incidence and outcome of neonatal encephalopathy according to …

Background: Microglia are key mediators of inflammation during perinatal brain injury. As
shown experimentally after inflammation-sensitized hypoxic ischemic (HI) brain injury …