Spinal cord stimulation: clinical efficacy and potential mechanisms

AD Sdrulla, Y Guan, SN Raja - Pain Practice, 2018 - Wiley Online Library
Spinal cord stimulation (SCS) is a minimally invasive therapy used for the treatment of
chronic neuropathic pain. SCS is a safe and effective alternative to medications such as …

Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action

J Caylor, R Reddy, S Yin, C Cui, M Huang… - Bioelectronic …, 2019 - Springer
Well-established in the field of bioelectronic medicine, Spinal Cord Stimulation (SCS) offers
an implantable, non-pharmacologic treatment for patients with intractable chronic pain …

Success using neuromodulation with BURST (SUNBURST) study: results from a prospective, randomized controlled trial using a novel burst waveform

T Deer, KV Slavin, K Amirdelfan, RB North… - … : Technology at the …, 2018 - Elsevier
Objective The purpose of the multicenter, randomized, unblinded, crossover Success Using
Neuromodulation with BURST (SUNBURST) study was to determine the safety and efficacy …

Conventional and novel spinal stimulation algorithms: hypothetical mechanisms of action and comments on outcomes

B Linderoth, RD Foreman - Neuromodulation: Technology at the Neural …, 2017 - Elsevier
Objective Spinal cord stimulation (SCS) emerged as a direct clinical spin-off from the Gate
Control Theory from 1965. Over the last decade, several new modes of SCS have appeared …

[HTML][HTML] Effects of rate on analgesia in kilohertz frequency spinal cord stimulation: results of the PROCO randomized controlled trial

SJ Thomson, M Tavakkolizadeh, S Love-Jones… - … : Technology at the …, 2018 - Elsevier
Objective The PROCO RCT is a multicenter, double-blind, crossover, randomized controlled
trial (RCT) that investigated the effects of rate on analgesia in kilohertz frequency (1–10 kHz) …

Burst and tonic spinal cord stimulation: different and common brain mechanisms

D De Ridder, S Vanneste - Neuromodulation: Technology at the Neural …, 2016 - Elsevier
Objective Spinal cord stimulation is commonly used to treat medically intractable pain.
Different stimulation designs are used to obtain pain suppression such as tonic stimulation …

Spinal cord stimulation in chronic pain: mode of action

R Vallejo, K Bradley, L Kapural - Spine, 2017 - journals.lww.com
Study Design. Literature review. Objective. A review of the literature that presents a
perspective on mechanisms of actions behind spinal cord stimulation (SCS) therapy for …

Mechanism of action in burst spinal cord stimulation: review and recent advances

K Chakravarthy, MA Fishman, X Zuidema… - Pain …, 2019 - academic.oup.com
Objective This is a comprehensive, structured review synthesizing and summarizing the
current experimental data and knowledge about the mechanisms of action (MOA) underlying …

The evolution of neuromodulation in the treatment of chronic pain: forward-looking perspectives

MA Fishman, A Antony, M Esposito, T Deer… - Pain …, 2019 - academic.oup.com
Background The field of neuromodulation is continually evolving, with the past decade
showing significant advancement in the therapeutic efficacy of neuromodulation procedures …

Burst and high frequency stimulation: underlying mechanism of action

S Ahmed, T Yearwood, D De Ridder… - Expert review of …, 2018 - Taylor & Francis
Introduction: Paresthesia-free spinal cord stimulation (SCS) techniques, such as burst and
high-frequency (HF) SCS, have been developed and demonstrated to be successful for …