Inhibitors of DNA binding and cell differentiation (Id) proteins are members of the large
family of the helix-loop-helix (HLH) transcription factors, but they lack any DNA-binding motif …

Id helix—loop—helix proteins function at a general level as positive regulators of cell growth
and as negative regulators of cell differentiation. They act as dominant—negative …

The inhibitor of DNA binding (Id) proteins are regulators of cell cycle and cell differentiation.
Of all Id family proteins, Id1 is mostly linked to tumorigenesis, cellular senescence as well as …

The Id family of helix–loop–helix (HLH) proteins are thought to affect the balance between
cell growth and differentiation by negatively regulating the function of basic–helix–loop …

Expression of the breast and ovarian cancer susceptibility gene BRCA1 is down-regulated
in sporadic breast and ovarian cancer cases. Therefore, the identification of genes involved …

Psoriasis is recognized as the most common T cell-mediated inflammatory disease in
humans. Genetic linkage to as many as six distinct disease loci has been established but the …

In a genome-wide small interfering RNA (siRNA) screen, we recently identified the interferon
(IFN)-inducible protein 35 (IFI35; also known as IFP35) as a factor required for vesicular …

The helix–loop–helix (HLH) protein Id2 is thought to affect the balance between cell growth
and differentiation by negatively regulating the function of basic‐helix–loop–helix (bHLH) …

Purpose: ID4 gene is a member of the inhibitor of DNA binding (ID) family proteins that
inhibit DNA binding of basic helix-loop-helix transcription factors. The epigenetic inactivation …

cDNA clones encoding the myogenic regulatory factors, myogenin, MyoD and myf‐5 were
cloned by reverse‐transcription polymerase chain reaction from larvae and embryos of the …