Ultrasound-responsive agents have shown great potential as targeted drug delivery agents,
effectively augmenting cell permeability and facilitating drug absorption. This review focuses …

The mechanical phenotype of a cell determines its ability to deform under force and is
therefore relevant to cellular functions that require changes in cell shape, such as migration …

Cancer initiation and progression follow complex molecular and structural changes in the
extracellular matrix and cellular architecture of living tissue. However, it remains poorly …

Current measurements of the biomechanical properties of cells require physical contact with
cells or lack subcellular resolution. Here we developed a label-free microscopy technique …

T cells are mechanosensitive but the effect of stiffness on their functions is still debated. We
characterize herein how human primary CD4+ T cell functions are affected by stiffness within …

The past decade has seen substantial growth in research into how changes in the
biomechanical and biophysical properties of cells and subcellular structures influence, and …

A cell undergoes many genetic and epigenetic changes as it transitions to malignancy.
Malignant transformation is also accompanied by a progressive loss of tissue homeostasis …

Cancer development and progression are closely associated with changes both in the
mechano-cellular phenotype of cancer and stromal cells and in the extracellular matrix …

Abstract αMβ2 integrin (complement receptor 3) is a major receptor for phagocytosis in
macrophages. In other contexts, integrins' activities and functions are mechanically linked to …

The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …