The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Conspectus A current issue in metal-catalyzed reactions is the search for highly efficient
transition-metal complexes affording high productivity and selectivity in a variety of …

Metallodrug-based photodynamic therapy (PDT) agents have demonstrated significant
superiority against cancers, while their different chirality-induced biological activities remain …

Alfred Werner was awarded the Nobel Prize in Chemistry just over 100 years ago. We recall
briefly the era in which he was working, his co-workers, and the equipment he used in his …

Aquation is often acknowledged as a necessary step for metallodrug activity inside the cell.
Hemilabile ligands can be used for reversible metallodrug activation. We report a new family …

Chiral natural biological molecules, such as nucleic acids and proteins, guide the research
of chiral compounds. Chiral metal-based drugs are currently an interesting and rapidly …

Eight new ruthenium and five new osmium p-cymene half-sandwich complexes have been
synthesized, characterized and evaluated for antimalarial activity. All complexes contain …

Besides worthy development in cancer therapy, cancer is still one of the leading causes of
death, worldwide. The future burden of cancer will probably be even larger because people …

There is an urgent need to discover new, selective compounds to add to the limited arsenal
of chemotherapeutics displaying selective toxicity for aggressive triple-negative breast …

Asymmetric transfer hydrogenation (ATH) is an important process in organic synthesis for
which the Noyori‐type RuII catalysts [(arene) Ru (Tsdiamine)] are now well established and …