With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Deep Learning (DL) has recently enabled unprecedented advances in one of the grand
challenges in computational biology: the half-century-old problem of protein structure …

With the development of modern high-throughput omic measurement platforms, it has
become essential for biomedical studies to undertake an integrative (combined) approach to …

MicroRNAs (miRNA) play critical roles in diverse biological processes of diseases. Inferring
potential disease-miRNA associations enable us to better understand the development and …

To fully utilize the advances in omics technologies and achieve a more comprehensive
understanding of human diseases, novel computational methods are required for integrative …

Metabolic reprogramming is a hallmark of cancer. However, systematic characterizations of
metabolites in triple-negative breast cancer (TNBC) are still lacking. Our study profiled the …

Cell differentiation and function are regulated across multiple layers of gene regulation,
including modulation of gene expression by changes in chromatin accessibility. However …

To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …

Medical artificial intelligence (AI) systems have been remarkably successful, even
outperforming human performance at certain tasks. There is no doubt that AI is important to …

Increased availability of high-throughput technologies has generated an ever-growing
number of omics data that seek to portray many different but complementary biological …