Ectosomes and exosomes: shedding the confusion between extracellular vesicles

E Cocucci, J Meldolesi - Trends in cell biology, 2015 - cell.com
Long-and short-distance communication can take multiple forms. Among them are
exosomes and ectosomes, extracellular vesicles (EVs) released from the cell to deliver …

Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation

D Brites, A Fernandes - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …

Challenges in the treatment of glioblastoma: multisystem mechanisms of therapeutic resistance

EK Noch, R Ramakrishna, R Magge - World neurosurgery, 2018 - Elsevier
Glioblastoma is one of the most lethal human cancers, with poor survival despite surgery,
radiation treatment, and chemotherapy. Advances in the treatment of this type of brain tumor …

Role of exosomes/microvesicles in the nervous system and use in emerging therapies

CPK Lai, XO Breakefield - Frontiers in physiology, 2012 - frontiersin.org
Extracellular membrane vesicles (EMVs) are nanometer sized vesicles, including exosomes
and microvesicles capable of transferring DNAs, mRNAs, microRNAs, non-coding RNAs …

Extracellular vesicles set the stage for brain plasticity and recovery by multimodal signalling

DM Hermann, L Peruzzotti-Jametti, B Giebel… - Brain, 2024 - academic.oup.com
Extracellular vesicles (EVs) are extremely versatile naturally occurring membrane particles
that convey complex signals between cells. EVs of different cellular sources are capable of …

Roles of microvesicles in tumor progression and clinical applications

S Zhu, S Li, M Yi, N Li, K Wu - International Journal of …, 2021 - Taylor & Francis
Microvesicles are extracellular vesicles with diameter ranging from 100 to 1000 nm that are
secreted by tumor cells or other cells in the tumor microenvironment. A growing number of …

Effects of glioblastoma-derived extracellular vesicles on the functions of immune cells

OE Musatova, YP Rubtsov - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Glioblastoma is the most aggressive variant of glioma, the tumor of glial origin which
accounts for 80% of brain tumors. Glioblastoma is characterized by astoundingly poor …

Glioblastoma multiforme-derived extracellular vesicles drive normal astrocytes towards a tumour-enhancing phenotype

S Oushy, JE Hellwinkel, M Wang… - … of the Royal …, 2018 - royalsocietypublishing.org
Glioblastoma multiforme (GBM) is a devastating tumour with abysmal prognoses. We
desperately need novel approaches to understand GBM biology and therapeutic …

Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease

DM Mallawaaratchy, S Hallal, B Russell, L Ly… - Journal of neuro …, 2017 - Springer
Extracellular vesicles (EVs) play key roles in glioblastoma (GBM) biology and represent
novel sources of biomarkers that are detectable in the peripheral circulation. Despite this …

The role of microvesicles and its active molecules in regulating cellular biology

YM Lv, J Tan, Y Miao, Q Zhang - Journal of Cellular and …, 2019 - Wiley Online Library
Cell‐derived microvesicles are membrane vesicles produced by the outward budding of the
plasma membrane and released by almost all types of cells. These have been considered …