Recent advancements in subcellular proteomics: growing impact of organellar protein niches on the understanding of cell biology

V Bhushan, A Nita-Lazar - Journal of proteome research, 2024‏ - ACS Publications
The mammalian cell is a complex entity, with membrane-bound and membrane-less
organelles playing vital roles in regulating cellular homeostasis. Organellar protein niches …

Advances in spatial proteomics: Map** proteome architecture from protein complexes to subcellular localizations

LM Breckels, C Hutchings, KD Ingole, S Kim… - Cell Chemical …, 2024‏ - cell.com
Proteins are responsible for most intracellular functions, which they perform as part of higher-
order molecular complexes, located within defined subcellular niches. Localization is both …

From cancer therapy to cardiac safety: the role of proteostasis in drug-induced cardiotoxicity

X Qian, M Yao, J Xu, N Dong, S Chen - Frontiers in Pharmacology, 2024‏ - frontiersin.org
Drug-induced cardiotoxicity (DICT) poses a significant challenge in the prognosis of cancer
patients, particularly with the use of antineoplastic agents like anthracyclines and targeted …

[HTML][HTML] An Extensive Atlas of Proteome and Phosphoproteome Turnover Across Mouse Tissues and Brain Regions

W Li, A Dasgupta, K Yang, S Wang… - …, 2024‏ - pmc.ncbi.nlm.nih.gov
Understanding how proteins in different mammalian tissues are regulated is central to
biology. Protein abundance, turnover, and post-translational modifications like …

[PDF][PDF] Application of Spatial Omics in the Cardiovascular System

Y Hu, H Jia, H Cui, J Song - Research‏ - spj.science.org
Cardiovascular diseases constitute a significant threat to global health and the emergence
of spatial omics technologies has revolutionized cardiovascular research. This review …