Light is necessary for life, and artificial light improves visual performance and safety, but
there is an increasing concern of the potential health and environmental impacts of light …

The suprachiasmatic nucleus (SCN) is the primary circadian pacemaker in mammals.
Individual SCN neurons in dispersed culture can generate independent circadian …

Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to …

Our understanding of the neural control of sleep in large part parallels the history of
neuroscience. As new tools and methodologies have become available to the research …

Although the mammalian rest-activity cycle is controlled by a" master clock" in the
suprachiasmatic nucleus (SCN) of the hypothalamus, it is unclear how firing of individual …

The suprachiasmatic nucleus (SCN) of the hypothalamus is the site of the master circadian
pacemaker in mammals. The individual cells of the SCN are capable of functioning …

This review consolidates research employing human correlational and experimental work
across brain and body with experimental animal models to provide a more complete …

Abstract Background Bipolar Disorder is characterized by episodes running the full mood
spectrum, from mania to depression. Between mood episodes, residual symptoms remain …

Background: Diagnosing narcolepsy without cataplexy is often a challenge as the symptoms
are nonspecific, current diagnostic tests are limited, and there are no useful biomarkers. In …

Health impairments, including reproductive issues, are associated with working nights or
rotating shifts. For example, shift work has been associated with an increased risk of …