Motor skills are required for activities of daily living. Transcranial direct current stimulation
(tDCS) applied in association with motor skill learning has been investigated as a tool for …

Neurodegenerative disorders (NDs) affect essential functions not only in the CNS, but also
cause persistent gut dysfunctions, suggesting that they have an impact on both CNS and gut …

Visuomotor adaptation has been thought to be an implicit process that results when a
sensory-prediction error signal is used to update a forward model. A striking feature of …

Background Huntington's disease (HD) is an autosomal dominant, fully penetrant,
neurodegenerative disease that most commonly affects adults in mid-life. Our aim was to …

On the basis of brain imaging studies, Doyon and Ungerleider recently proposed a model
describing the cerebral plasticity that occurs in both cortico–striatal and cortico–cerebellar …

Polyglutamine expansion (polyQ) in the protein huntingtin is pathogenic and responsible for
the neuronal toxicity associated with Huntington's disease (HD). Although wild-type …

This review discusses the cerebral plasticity, and the role of the cortico-striatal system in
particular, observed as one is learning or planning to execute a newly learned motor …

Smoothness is characteristic of coordinated human movements, and stroke patients'
movements seem to grow more smooth with recovery. We used a robotic therapy device to …

The role of the cerebellum in motor control and learning has been largely inferred from the
effects of cerebellar damage. Recent work shows that cerebellar damage produces greater …

Locomotor adaptability ranges from the simple and fast-acting to the complex and long-
lasting and is a requirement for successful mobility in an unpredictable environment. Several …