The epithelial lining of the airway forms the first barrier against environmental insults, such
as inhaled cigarette smoke, which is the primary risk factor for the development of chronic …

β-catenin (encoded by CTNNB1) is a subunit of the cell surface cadherin protein complex
that acts as an intracellular signal transducer in the WNT signaling pathway; alterations in its …

Adherens junctions and Tight junctions comprise two modes of cell–cell adhesion that
provide different functions. Both junctional complexes are proposed to associate with the …

This review is dedicated to E-cadherin, a calcium-dependent cell-cell adhesion molecule
with pivotal roles in epithelial cell behavior, tissue formation, and suppression of cancer. As …

▪ Abstract Src family protein tyrosine kinases are activated following engagement of many
different classes of cellular receptors and participate in signaling pathways that control a …

β‐catenin is a central component of the cadherin cell adhesion complex and plays an
essential role in the Wingless/Wnt signaling pathway. In the current model of this pathway …

Methacrylated hyaluronic acid (HA) hydrogels provide a backbone polymer with which
mesenchymal stem cells (MSCs) can interact through several cell surface receptors that are …

In a recently developed human breast cancer model, treatment of tumor cells in a 3-
dimensional culture with inhibitory ß1-integrin antibody or its Fab fragments led to a striking …

Junctional structures maintain the integrity of the endothelium. Recent studies have shown
that, as well as promoting cell–cell adhesion, junctions might transfer intracellular signals …

Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …