Considerable efforts have been exerted to implement Pharmacogenomics (PGx), the study
of interindividual variations in DNA sequence related to drug response, into routine clinical …

Background The benefit of pharmacogenetic testing before starting drug therapy has been
well documented for several single gene–drug combinations. However, the clinical utility of …

Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

Importance Implementation of pharmacogenetic testing to guide drug prescribing has
potential to improve drug response and prevent adverse events. Robust data exist for more …

Background Clinical pharmacogenomics uses genetic information to guide optimal drug
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …

Background The clinical implementation of pharmacogenomics (PGx) could be one of the
first milestones towards realizing personalized medicine in routine care. However, its …

Pre‐emptive pharmacogenetics (PG x) testing of a panel of germline genetic variants
represents a new model for personalized medicine. Clinical impact of PG x testing is …

Drug interactions are a well-known cause of adverse drug events, and drug interaction
databases can help the clinician to recognize and avoid such interactions and their adverse …

Contamination is a potential problem in the study of ancient proteins, either from prior
handling of the sample, laboratory consumables, or cross-sample carryover from mass …

Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and
more effective by utilizing genetic patient data for drug dosing and selection. However …