Update on the role of muscle in the genesis and management of knee osteoarthritis

KL Bennell, TV Wrigley, MA Hunt… - Rheumatic …, 2013 - rheumatic.theclinics.com
The muscles of the lower limb, particularly the quadriceps, play an important role in the
genesis and management of knee osteoarthritis (OA). At the knee, muscles function to …

Establishing outcome measures in early knee osteoarthritis

CA Emery, JL Whittaker, A Mahmoudian… - Nature Reviews …, 2019 - nature.com
The classification and monitoring of individuals with early knee osteoarthritis (OA) are
important considerations for the design and evaluation of therapeutic interventions and …

[HTML][HTML] CEINMS: A toolbox to investigate the influence of different neural control solutions on the prediction of muscle excitation and joint moments during dynamic …

C Pizzolato, DG Lloyd, M Sartori, E Ceseracciu… - Journal of …, 2015 - Elsevier
Personalized neuromusculoskeletal (NMS) models can represent the neurological,
physiological, and anatomical characteristics of an individual and can be used to estimate …

Subject-specific knee joint geometry improves predictions of medial tibiofemoral contact forces

P Gerus, M Sartori, TF Besier, BJ Fregly, SL Delp… - Journal of …, 2013 - Elsevier
Estimating tibiofemoral joint contact forces is important for understanding the initiation and
progression of knee osteoarthritis. However, tibiofemoral contact force predictions are …

Biomechanical deviations during level walking associated with knee osteoarthritis: a systematic review and meta‐analysis

K Mills, MA Hunt, R Ferber - Arthritis care & research, 2013 - Wiley Online Library
Objective To identify which gait deviations are consistently associated with knee
osteoarthritis (KOA) and how these are influenced by disease severity, the involved …

[HTML][HTML] Relationship between knee joint contact forces and external knee joint moments in patients with medial knee osteoarthritis: effects of gait modifications

RE Richards, MS Andersen, J Harlaar… - Osteoarthritis and …, 2018 - Elsevier
Objective To evaluate 1) the relationship between the knee contact force (KCF) and knee
adduction and flexion moments (KAM and KFM) during normal gait in people with medial …

Gait analysis of patients with knee osteoarthritis highlights a pathological mechanical pathway and provides a basis for therapeutic interventions

J Favre, BM Jolles - EFORT open reviews, 2016 - eor.bioscientifica.com
Knee osteoarthritis (OA) is a painful and incapacitating disease affecting a large portion of
the elderly population, for which no cure exists. There is a critical need to enhance our …

Increased duration of co-contraction of medial knee muscles is associated with greater progression of knee osteoarthritis

PW Hodges, W van den Hoorn, TV Wrigley, RS Hinman… - Manual Therapy, 2016 - Elsevier
Background As knee osteoarthritis (OA) cannot be cured, treatments that slow structural
disease progression are a priority. Knee muscle activation has a potential role in OA …

An omnidirectionally stretchable piezoelectric nanogenerator based on hybrid nanofibers and carbon electrodes for multimodal straining and human kinematics …

S Siddiqui, HB Lee, DI Kim, LT Duy… - Advanced Energy …, 2018 - Wiley Online Library
Stretchable piezoelectric nanogenerators (SPENGs) for human kinematics energy
harvesting have limited use due to the low stretchability or mechanical robustness and the …

A systematic review on changed biomechanics of lower extremities in obese individuals: a possible role in development of osteoarthritis

J Runhaar, BW Koes, S Clockaerts… - Obesity …, 2011 - Wiley Online Library
Obesity has been identified as a risk factor for osteoarthritis. For the weight‐bearing joints,
the combination of increased load and changed joint biomechanics could be regarded as …