Mutations and evolution of the SARS-CoV-2 spike protein

N Magazine, T Zhang, Y Wu, MC McGee, G Veggiani… - Viruses, 2022 - mdpi.com
The SARS-CoV-2 spike protein mediates target recognition, cellular entry, and ultimately the
viral infection that leads to various levels of COVID-19 severities. Positive evolutionary …

The hallmarks of COVID-19 disease

D Tang, P Comish, R Kang - PLoS pathogens, 2020 - journals.plos.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that
has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a …

The protein expression profile of ACE2 in human tissues

F Hikmet, L Méar, Å Edvinsson, P Micke… - Molecular systems …, 2020 - embopress.org
The novel SARS‐coronavirus 2 (SARS‐CoV‐2) poses a global challenge on healthcare and
society. For understanding the susceptibility for SARS‐CoV‐2 infection, the cell type‐specific …

Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study

AA Elfiky - Life sciences, 2020 - Elsevier
Aims A new human coronavirus (HCoV), which has been designated SARS-CoV-2, began
spreading in December 2019 in Wuhan City, China causing pneumonia called COVID-19 …

Anti-HCV, nucleotide inhibitors, repurposing against COVID-19

AA Elfiky - Life sciences, 2020 - Elsevier
Aims A newly emerged Human Coronavirus (HCoV) is reported two months ago in Wuhan,
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …

The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice

EM Rhea, AF Logsdon, KM Hansen, LM Williams… - Nature …, 2021 - nature.com
It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes
coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome …

COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review

A Cavezzi, E Troiani, S Corrao - Clinics and practice, 2020 - pmc.ncbi.nlm.nih.gov
Coronavirus disease-19 (COVID-19) has been regarded as an infective-inflammatory
disease, which affects mainly lungs. More recently, a multi-organ involvement has been …

Pathophysiology of COVID-19: why children fare better than adults?

N Dhochak, T Singhal, SK Kabra, R Lodha - The Indian Journal of …, 2020 - Springer
The world is facing Coronavirus Disease-2019 (COVID-19) pandemic, which is causing a
large number of deaths and burden on intensive care facilities. It is caused by Severe Acute …

The 2019–2020 novel coronavirus (severe acute respiratory syndrome coronavirus 2) pandemic: A joint american college of academic international medicine-world …

SP Stawicki, R Jeanmonod, AC Miller… - Journal of global …, 2020 - journals.lww.com
What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in
December 2019, was later determined to be coronavirus disease 2019 (COVID-19). The …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) infection, has emerged in China in December 2019 …