Features of third generation photosensitizers used in anticancer photodynamic therapy

IS Mfouo-Tynga, LD Dias, NM Inada… - … and photodynamic therapy, 2021 - Elsevier
Cancer remains a main public health issue and the second cause of mortality worldwide.
Photodynamic therapy is a clinically approved therapeutic option. Effective photodynamic …

Quest for novel chemical entities through incorporation of silicon in drug scaffolds

R Ramesh, DS Reddy - Journal of Medicinal Chemistry, 2017 - ACS Publications
In order to optimize a lead molecule for further development, bioisosteric replacements are
generally adopted as one of the strategies. Silicon appears to be the right choice as a …

Reactive oxygen species (ROS): utilizing injectable antioxidative hydrogels and ROS-producing therapies to manage the double-edged sword

Z He, Q Xu, B Newland, R Foley, I Lara-Sáez… - Journal of Materials …, 2021 - pubs.rsc.org
Reactive oxygen species (ROS) are generated in cellular metabolism and are essential for
cellular signalling networks and physiological functions. However, the functions of ROS are …

Photodynamic therapy for metastatic melanoma treatment: A review

C Naidoo, CA Kruger… - Technology in cancer …, 2018 - journals.sagepub.com
This review article is based on specifically targeted nanoparticles that have been used in the
treatment of melanoma. According to the Skin Cancer Foundation, within 2017 an estimated …

Combined treatments with photodynamic therapy for non-melanoma skin cancer

SR Lucena, N Salazar, T Gracia-Cazaña… - International journal of …, 2015 - mdpi.com
Non-melanoma skin cancer (NMSC) is the most common form of cancer in the Caucasian
population. Among NMSC types, basal cell carcinoma (BCC) has the highest incidence and …

[HTML][HTML] A promising natural anthraquinones mediated by photodynamic therapy for anti-cancer therapy

M Nowak-Perlak, P Ziółkowski, M Woźniak - Phytomedicine, 2023 - Elsevier
Background Experimental studies emphasize the therapeutic potential of plant-derived
photosensitizers used in photodynamic therapy. Moreover, several in vitro and in vivo …

Phthalocyanine in perovskite solar cells: A review

E Rezaee, D Khan, S Cai, L Dong, H **ao… - Materials Chemistry …, 2023 - pubs.rsc.org
Presently, due to the rapid development of perovskite solar cells (PSCs), their
commercialization is not only attractive but perhaps the only choice to replace both thin film …

[HTML][HTML] Tumor cell-activated “Sustainable ROS Generator” with homogeneous intratumoral distribution property for improved anti-tumor therapy

J Liu, X Zhao, W Nie, Y Yang, C Wu, W Liu, K Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) holds a number of advantages for tumor therapy. However, its
therapeutic efficiency is limited by non-sustainable reactive oxygen species (ROS) …

Effective gold nanoparticle-antibody-mediated drug delivery for photodynamic therapy of lung cancer stem cells

A Crous, H Abrahamse - International Journal of Molecular Sciences, 2020 - mdpi.com
Cancer stem cells (CSCs) are a leading contributor to lung cancer mortality rates. CSCs are
responsible for tumor growth and recurrence through inhibition of drug-induced cell death …

Mechanisms of photodynamic therapy

D Sharma, S Singh, P Kumar, GK Jain… - Nanomaterials for …, 2023 - Elsevier
Photodynamic therapy (PDT) is an established photochemical treatment. PDT uses
photosensitizer (PSs) that are excited by light at a particular wavelength after being …